As the offshore energy industry begins to develop wind farms in areas of deeper water, the use of traditional foundations such as shallow foundation and driven hollow steel tube piles becomes uneconomical. The deployment of floating turbines and continued development of novel/efficient anchoring systems for these structures will be an important factor in the continued growth of the sector. This paper presents an investigation carried out as part of a proof-of-concept for a novel “bi-wing anchor”. This design will allow a plate anchor to be dropped through the water column and then penetrate the seabed under its own weight. The anchor will then be dragged causing it to embed further into the seabed and provide a greater holding capacity. This paper focuses on experimental as well as analysis of the drag embedment behaviour during the installation and pullout phases. The physical modelling investigations were carried out in a transparent clay-surrogate which enabled observation of the anchor’s orientation during installation. The predictions using analytical modelling showed good agreement with the observed behaviour at varying embedment ratios.

This paper presents data from an initial development stage of an 'umbrella anchor' concept. The anchor can be pushed into a sand deposit in a folded arrangement to reduce installation loads. When a pull-out load is applied to the mooring line, the anchor deploys to create a large embedded plate anchor. Physical modelling was carried out in a saturated sand bed with the anchor installed at depths of up to 1.6 m and loaded vertically. During installation, liquefaction was generated at the tip of the anchor to reduce the penetration resistance. This enabled the anchor to be installed quickly and accurately to a target depth. The anchor could provide pull-out resistances comparable to an anchor that has been wished-in-place at similar depths. The observed behaviour provided encouraging preliminary results and suggests that, with further development and analysis, the concept could potentially be used for commercial applications.

Precision medicine is a new frontier in healthcare that uses scientific methods to customize medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person. In cardiovascular health, precision medicine has emerged as a promising paradigm to enable cost-effective solutions that improve quality of life and reduce mortality rates. However, the exact role in precision medicine for human heart modeling has not yet been fully explored. Here, we discuss the challenges and opportunities for personalized human heart simulations, from diagnosis to device design, treatment planning, and prognosis. With a view toward personalization, we map out the history of anatomic, physical, and constitutive human heart models throughout the past three decades. We illustrate recent human heart modeling in electrophysiology, cardiac mechanics, and fluid dynamics and highlight clinically relevant applications of these models for drug development, pacing lead failure, heart failure, ventricular assist devices, edge-to-edge repair, and annuloplasty. With a view toward translational medicine, we provide a clinical perspective on virtual imaging trials and a regulatory perspective on medical device innovation. We show that precision medicine in human heart modeling does not necessarily require a fully personalized, high-resolution whole heart model with an entire personalized medical history. Instead, we advocate for creating personalized models out of population-based libraries with geometric, biological, physical, and clinical information by morphing between clinical data and medical histories from cohorts of patients using machine learning. We anticipate that this perspective will shape the path toward introducing human heart simulations into precision medicine with the ultimate goals to facilitate clinical decision making, guide treatment planning, and accelerate device design.