Diabetic retinopathy (DR) is a leading cause of permanent vision loss worldwide. It refers to irreversible retinal damage caused due to elevated glucose levels and blood pressure. Regular screening for DR can facilitate its early detection and timely treatment. Neural network-based DR classifiers can be leveraged to achieve such screening in a convenient and automated manner. However, these classifiers suffer from reliability issue where they exhibit strong performance during development but degraded performance after deployment. Moreover, they do not provide supplementary information about the prediction outcome, which severely limits their widespread adoption. Furthermore, energy-efficient deployment of these classifiers on edge devices remains unaddressed, which is crucial to enhance their global accessibility. In this paper, we present a reliable and energy-efficient hardware for DR detection, suitable for deployment on edge devices. We first develop a DR classification model using custom training data that incorporates diverse image quality and image sources along with improved class balance. This enables our model to effectively handle both on-field variations in retinal images and minority DR classes, enhancing its post-deployment reliability. We then propose a pseudo-binary classification scheme to further improve the model performance and provide supplementary information about the model prediction. Additionally, we present an energy-efficient hardware design for our model using memristor-based computation-in-memory, to facilitate its deployment on edge devices. Our proposed approach achieves reliable DR classification with three orders of magnitude reduction in energy consumption over state-of-the-art hardware platforms.

Computation-in-memory (CIM) paradigm leverages emerging memory technologies such as resistive random access memories (RRAMs) to process the data within the memory itself. This alleviates the memory-processor bottleneck resulting in much higher hardware efficiency compared to von-Neumann architecture-based conventional hardware. Hence, CIM becomes an attractive alternative for applications like neural networks which require a huge number of data transfer operations in conventional hardware. CIM-based neural networks typically employ bit-slicing scheme which represents a single neural weight using multiple RRAM devices (called slices) to meet the high bit-precision demand. However, such neural networks suffer from significant accuracy degradation due to non-zero Gmin error where a zero weight in the neural network is represented by an RRAM device with a non-zero conductance. This paper proposes an unbalanced bit-slicing scheme to mitigate the impact of non-zero Gmin error. It achieves this by allocating appropriate sensing margins for different slices based on their binary positions. It also tunes the sensing margins to meet the demands of either high accuracy or energy-efficiency. The sensing margin allocation is supported by 2's complement arithmetic which further reduces the influence of non-zero Gmin error. Simulation results show that our proposed scheme achieves up to 7.3× accuracy and up to 7.8× correct operations per unit energy consumption compared to state-of-the-art.

Timely detection of cardiac arrhythmia characterized by abnormal heartbeats can help in the early diagnosis and treatment of cardiovascular diseases. Wearable healthcare devices typically use neural networks to provide the most convenient way of continuously monitoring heart activity for arrhythmia detection. However, it is challenging to achieve high accuracy and energy efficiency in these smart wearable healthcare devices. In this work, we provide architecture-level solutions to deploy neural networks for cardiac arrhythmia classification. We have created a hierarchical structure after analyzing various neural network topologies where only required network components are activated to improve energy efficiency while maintaining high accuracy. In our proposed architecture, we introduce a severity-based classification approach to directly help the users of the wearable healthcare device as well as the medical professionals. Additionally, we have employed computation-in-memory based hardware to improve energy efficiency and area consumption by leveraging in-situ data processing and scalability of emerging memory technologies such as resistive random access memory (RRAM). Simulation experiments conducted using the MIT-BIH arrhythmia dataset show that the proposed architecture provides high accuracy while consuming average energy of 0.11 $\mu$J per heartbeat classification and 0.11 mm2 area, thereby achieving 25× improvement in average energy consumption and 12× improvement in area compared to the state-of-the-art.

Resistive random access memory (RRAM) based computation-in-memory (CIM) architectures are attracting a lot of attention due to their potential in performing fast and energy-efficient computing. However, the RRAM variability and non-idealities limit the computing accuracy of such architectures, especially for multi-operand logic operations. This paper pro-poses a voltage-based differential referencing-in-array scheme that enables accurate two and multi-operand logic operations for RRAM-based CIM architecture. The scheme makes use of a 2T2R cell configuration to create a complementary bitcell structure that inherently acts also as a reference during the operation execution; this results in a high sensing margin. More-over, the variation-sensitive multi-operand (N)AND operation is implemented using complementary-input (N)OR operation to further improve its accuracy. Simulation results for a post-layout extracted 512x512 (256Kb) RRAM-based CIM array show that up to 56 operand (N)OR/(N)AND operation can be accurately and reliably performed as opposed to a maximum of 4 operands supported by state-of-the-art solutions, while offering up to 11.4X better energy-efficiency.

Emerging computation-in-memory (CIM) paradigm offers processing and storage of data at the same physical location, thus alleviating critical memory-processor communication bottlenecks suffered by conventional von-Neumann architecture. Storage of data in a CIM architecture is analog in nature and therefore computation is performed in analog domain i.e. inputs and outputs are analog values. Since the outside computing environment is digital, analog-to-digital converters (ADC) are utilized to perform the output data conversion. However, ADC designs are bulky, power-hungry circuits that are prone to design variations and therefore, play an important role in determining the computing efficiency of CIM architectures. In this paper, we present a scalable and reliable integrate and fire circuit ADC (SRIF-ADC) design for CIM architectures, suitable for stringent power and area constraints. We devise a technique to stabilize the node receiving analog inputs that allows more rows to be activated at the same time, thereby increasing the operand size of input vectors. This allows better scalability in terms of higher parallelism of operations. We employ a self-timed variation-aware design approach and design measures to drastically reduce read disturb of memristor devices that address reliability issues related to the ADC design. In addition, we present a compact, built-in sample-and-hold circuit to replace the large-sized capacitance and built-in weighting technique to alleviate the need for post-processing. For multiply-and-accumulate (MAC) operation, our simulation results show that we can improve the computational parallelism by 3X as well as ADC conversion speed and energy efficiency are improved by 2X and 11.6X, respectively, compared to the state-of-the-art design.

With the rise of the Internet of Things (IoT), a huge market for so-called smart edge-devices is foreseen for millions of applications, like personalized healthcare and smart robotics. These devices have to bring smart computing directly where the data is generated, while coping with the limited energy budget. Conventional von-Neumann architecture fail to meet these requirements due to e.g., memory-processor data transfer bottleneck. Memristor-based computation-in-memory (CIM) has the potential to realize smart local computing for highly parallel data-dominated AI applications by exploiting the inherent properties of the architecture and the physical characteristics of the memristors. This paper provides a broad overview of CIM architecture highlighting its potential and unique properties in enabling smart local computing. Moreover, it discusses design considerations of such architectures including both crossbar array as well as peripheral circuits; special attention is given to analog-to-digital converter (ADC), as it is the most critical unit of analog-based CIM operation e.g., vector-matrix multiplication (VMM). Finally, the paper outlines the potential future directions for CIM-based edge smart computing.