The endeavor to emulate the extraordinary efficiency and adaptability inherent in the human brain via spike-based neuromorphic computing presents significant potential across a diverse array of applications. The attainment of this objective necessitates the translation of biological principles into artificial systems, a task that continues to pose a complex challenge requiring a profound comprehension of the mechanisms by which neural systems produce robust computational outcomes. This tutorial paper provides a comprehensive overview of the foundational concepts and emerging design trends in spike-based neuromorphic computing, covering advances from materials and circuits to hardware architectures and learning mechanisms. It begins with an examination of key aspects of brain biology and their influence on neuromorphic design, followed by a brief discussion of biologically plausible neuron and synapse models. The paper then defines the core principles and defining attributes of neuromorphic computing, highlighting the trade-offs and design choices underlying current implementations. Building on these foundations, it explores the critical properties of neuromorphic systems, surveys a variety of learning algorithms, and reviews hardware-level realizations of bioinspired neurons and synapses. Subsequent sections discuss state-of-the-art spiking neural network architectures, mapping and compilation strategies, and representative application domains. By providing this end-to-end perspective, the article aims to guide the development of future neuromorphic systems that more closely emulate brain efficiency, scalability, and resilience.

Computation-in-Memory (CIM) architectures address the rising demand for energy-efficient artificial intelligence (AI) solutions, by minimizing costly data movements between memory and processor. Within such architectures, SRAM-based digital CIM is especially attractive as it preserves the advantages of CIM while avoiding analog complexity. Recent studies have revealed potential weaknesses in these architectures, particularly to power side-channel attacks (SCA) capable of extracting sensitive model parameters (e.g., neural network (NN) weights), which represent the intellectual property of CIM-based neural network systems. In this study, we propose and evaluate two countermeasures to secure SRAM-based CIM architectures against power attacks: (1) Balanced Obfuscated-path countermeasure, and (2) Glitch Aware countermeasure. To validate their effectiveness, we conducted a comprehensive power analysis that successfully demonstrated attacks against an unprotected implementation. Our experimental results demonstrate that both countermeasures significantly improve resistance to power attacks. Although the Balanced Obfuscated-path offers better area overhead and run-time performance, the Glitch Aware approach achieves higher protection against advanced attacks, making each suitable for different design constraints.

Although offering great potential for energy-efficient edge-AI, memristor-based CIM accelerators are severely hindered by IR drop induced errors. To tackle this, we propose a low-cost mitigation technique by first quantifying the impact of IR drop on the accuracy. Then, a mitigation strategy is developed to compensate for IR drop-induced inference accuracy reduction by combining an optimized mapping scheme with a fine-tuned calibration of the ADC. Results show the proposed solution can effectively mitigate IR drop with a negligible overhead.

Vector–matrix multiplication (VMM), implemented through multiply–accumulate (MAC) operations, represents the dominant computational primitive in many artificial intelligence (AI) workloads. When executed on conventional von Neumann architectures, VMM operations suffer from important energy consumption and latency due to the separation between memory and processing units. To overcome these limitations, crossbar arrays built from Resistive Random Access Memory (RRAM) cells have been proposed for accelerating VMM computations. In this work, we investigate the key optimization trade-offs associated with implementing RRAM-based neural networks for classification applications. A simple two-layer neural network is first defined and trained in software to generate the weight matrices and bias parameters. Next, three hardware implementation scenarios are evaluated depending on whether negative floating-point numbers are used: Positive Weights Only (PWO), Positive and Negative Weights Only (PNWO), and Positive and Negative Weights with Biases (PNWB). The different implementations are analyzed at the hardware level by examining classification accuracy, energy efficiency, latency, and area overhead. The study further incorporates important RRAM limitations, including restricted conductance range and device variability. Hardware results show that the PWO scenario offers the lowest energy consumption (189 fJ/MAC) and area overhead but results in the lowest accuracy. PNWO and PNWB significantly improve accuracy (+177% and +180%) but increase energy consumption (+63% and +87%) and area (×2 and ×2.1). Under variability effects, PWO achieves better accuracy (94.65%), followed by PNWO (93.11%) and PNWB (92.11%).

Theoretically speaking, Majority logic, originally proposed in the ^{\prime }70s, enables more compact and efficient arithmetic implementations than the conventional Boolean counterpart. Nonetheless, CMOS technology based Majority logic realizations remain challenging, as standard transistor-based approaches are unable to directly exhibit majority behavior. However, recent exploration on beyond CMOS technologies created a resurgence of the interest in majority logic. In this work, we propose and analyze a novel approach towards the 3-input Majority gate (MAJ3) implementation by means of piezoelectric materials. By leveraging their intrinsic electromechanical properties, we convert the digital input signals into mechanical deformations, which are accumulated in a transfer layer. Subsequently, we transform the combined deformation back to the electric domain with a piezoelectronics element properly designed to perform majority functionality. We first present the underlying principles behind our proposal with a short introduction on majority logic, piezoelectronics, and the utilized simulation framework. Afterwards we introduce the proposed piezoelectric 3-input Majority gate (piezo-MAJ3) and strategies for optimizing its behavior and performance. We also detail the material parameters and structural design impact on device performance by utilizing both analytical discussion and physics-based simulations. Finally, we shortly highlight how our proposal can be directly integrated into CMOS circuits and compare the piezo-MAJ3 potential cost and performance with the ones of state of the art implementations. Our results indicate that when compared with its CMOS counterpart, the piezo-MAJ3 gate requires half the area, it is 7x faster, while reducing with 44% the energy consumption.

Analog Compute-in-Memory (CIM), leveraging non-volatile memristive devices to perform in-place computations in the analog domain, holds great potential to efficiently accelerate vector-matrix multiplications (VMM) and realize AI (Artificial Intelligence) at the edge. However, the data converters in such architectures often trade-off accuracy for high energy and area overheads, practically limiting the benefits of CIM. In this work, we present SABCIM, an array-periphery co-design approach for CIM that enables accurate computation as well as digitization of analog VMM outputs with high energy efficiency and competitive area overhead. By leveraging complementary input activations and data storage, each crossbar column generates differential analog output corresponding to the vector-vector multiplication (VVM) result, while inherently addressing underlying non-idealities. This is digitized using a compact, dual-ramp voltage-to-time converter (VTC)-based analog-to-digital converter (ADC). Benchmark results indicate that our work achieves up to 19.6 × higher energy efficiency compared to state-of-the-art (SOTA), while maintaining comparable accuracies.

Resistive random-access memory (RRAM)-based computation-in-memory (CIM) architectures offer a promising solution to meet the stringent energy efficiency demands of executing artificial intelligence (AI) algorithms directly on edge devices. However, these architectures suffer from the read-disturb problem, which can lead to accumulated computational errors over time. To maintain the required level of computational accuracy, conventional approaches rely on a static reprogramming process after a predefined number of read cycles, necessitating large counters and resulting in inefficiencies. This paper presents experimental results using real RRAM devices to analyze the read-disturb effect and builds on these insights to propose a circuit-level detection methodology for real-time monitoring of conductance drifts. The proposed method initiates reprogramming only when the device drift exceeds a defined threshold and reprogramming is actually needed. Additionally, an analytical method is developed to determine the minimum conductance state ratio needed to meet reliable detection criteria. Based on this foundation, the proposed detection technique is further optimized for dynamic identification of read-disturb effects. Experiment-augmented SPICE simulation results, using a calibrated model implemented in TSMC 40 nm CMOS technology, validate the functionality and effectiveness of the proposed detection approach. These results demonstrate its potential to improve both the reliability and efficiency of RRAM-based CIM architectures that provide up to a 4x improvement in energy-efficiency compared to traditional periodic reprogramming methods.

Computing-in-Memory (CIM) architectures using memristive crossbar arrays enable energy-efficient AI acceleration. Analog non-idealities, such as IR drop and nonlinearity, impose design constraints that existing simulators cannot capture and thus explore effectively. Current approaches sacrifice either modeling accuracy or simulation speed, preventing systematic design space exploration. In this paper we propose X-Sim, a crossbar simulator that resolves this trade-off through a modular architecture. Our approach decouples device physics from circuit analysis using a fixed-point scheme, avoiding expensive Jacobian computations while preserving device fidelity. X-Sim delivers SPICE-level accuracy (< 1% error) with up to 200× speedup over physics-based simulators. This enables quick and systematic design space exploration across thousands of configurations, guiding reliable system design. X-Sim will be released as open source.

Physics-based compact models for emerging non-volatile memories (NVMs) are often limited by the complex interactions of microscopic domains and defects that are difficult to capture analytically, resulting in reduced accuracy and simulation efficiency. To address this challenge, a machine learning (ML)-based approach is proposed using artificial neural networks (ANNs) trained entirely on device measurement data, enabling a direct translation of fabrication characteristics into SPICE-compatible circuit models. The resulting models achieve high accuracy (MSE: 0.724, adjusted R² : 0.998), significantly outperforming physics-based baselines with an 18× lower MSE for polarization and a two-order-of-magnitude precision improvement in FeFET current simulation, while accurately capturing the wake-up process. Furthermore, the model demonstrates robust out-of-distribution (OOD) extrapolation to unseen ferroelectric thicknesses and a 33.7% improvement in simulation speed. These results validate the ML-based approach as a highly efficient, SPICE-compatible solution for next-generation memory.

Addressing non-idealities in Resistive Random Access Memories (RRAMs) is crucial for their successful commercialization. For example, the inherent resistance drift that occurs during consecutive read operations can induce Read Disturb Faults (RDF), leading to functional errors. This paper analyzes and characterizes the resistance drift and the RDF based on data measurements and presents a physics-based RRAM compact model that incorporates these non-idealities. Additionally, an in-field mitigation scheme is proposed, leveraging bidirectional read operations to balance the resistance. The scheme is implemented and validated through circuit simulations, both for RRAM used as memory and for RRAM-based computation-in-memory microarchitectures for deep neural networks. The results demonstrate that RRAM without any mitigation scheme can start failing after 8,000 consecutive reads, while our mitigation scheme ensures that the memory remains functional even after 10⁶ consecutive reads. Furthermore, the results indicate that using the MNIST dataset as a case study, the accuracy can drop significantly from 86% to as low as 12.5% without any mitigation scheme. In contrast, the proposed mitigation scheme improves this accuracy up to 84.2%.

Approximately one-third of individuals with chronic epilepsy, a condition resulting from uncontrolled brain activity, do not respond to medication. Animal models are widely used to investigate the mechanism underlying epilepsy, so better drug treatments can be developed for this disease. In such studies, epileptiform activity, assessed by EEG recordings, can be used as a marker for the development of the disease. However, the analysis of EEG recordings is typically done manually, which is time-consuming, subject to observer bias, error-prone, and lacks consistency and efficiency. In this paper, we develop a novel automated methodology for detecting and classifying epileptiform activity, which is tested using the intrahippocampal kainic acid (IHKA) mouse model, a representation of human temporal lobe epilepsy. For that, EEG/LFP recordings are obtained from biological experiments using the IHKA mouse model for data acquisition. We use a spike detection method that combines an improved version of the nonlinear energy operator (NEO) with the automatic NEO thresholding (ANT) algorithm. The proposed method is implemented in Python as an automated and time-efficient algorithm, given its adaptability to different spike and epileptiform event criteria, making it suitable for use in preclinical and potentially future clinical studies. Using our proposed methodology, we achieve a 93.1% accuracy in detecting epileptiform events and a 95.8% accuracy in classification. Moreover, the time for analysis of EEG recordings was reduced by 98.8% compared to manual analysis. Additionally, to demonstrate the potential of the algorithm for brain–machine interfaces (BMI) applications, we develop a hardware architecture and implement it using both an application-specific integrated circuit (ASIC) and a field programmable gate array (FPGA). The FPGA shows the feasibility of near real-time implementation, and for our ASIC implementation, we achieve a post-layout area of 9114 µm² with a dynamic power consumption of 16.09 μW using TSMC 40 nm technology.

The IEEE European Test Symposium (ETS) has been facilitating progress in electronic systems testing since its launch in 1996. On the occasion of its 30th anniversary, this collaborative paper gathers sections by 21 ETS teams to outline their influential ideas and milestones. Each team's section highlights historical perspective, current research, frameworks and projects as well as forward-looking research agendas in the area of electronic-based circuits and systems testing, reliability, safety, security and validation. This anniversary summary documents how research of various ETS teams, exemplifying the test community, has been evolving and transitioning from concepts to practical standards and Electronic Design Automation (EDA) tools and flows. This legacy is a strong base to drive the next generation of advances in electronic systems testing.