D. Dodou
Please Note
42 records found
1
This study examines human driver decision-making in a narrow-passage gap-acceptance task, an interaction scenario characterised by ambiguity of priority and described by interdependent kinematic and visual information. Behavioural data from laboratory ($N=36$) and ($N=175$) online experiments were analysed to assess whether decision dynamics generalise across populations with differing variability and experimental control.
Across datasets, decision behaviour showed systematic dependencies on kinematic conditions, with increased reaction times (RTs) and choice variability in ambiguous situations. Longitudinal kinematics-based drift diffusion models (LK-DDMs) captured both decision proportions and reaction-time distributions in the narrow passage task and generalised across datasets with differing coverage of the experimental conditions, including lab and online data. The same accumulation framework transferred to a related decision-making task, indicating that the inferred dynamics are not task-specific. Incorporating visual looming in the drift function yielded selective improvements in short-distance Wait decisions, without global gains in reaction-time accuracy.
OSF link: https://osf.io/5d6em/overview?view_only=18580aa504f24d92a55cbccf53bb5deb ...
This study examines human driver decision-making in a narrow-passage gap-acceptance task, an interaction scenario characterised by ambiguity of priority and described by interdependent kinematic and visual information. Behavioural data from laboratory ($N=36$) and ($N=175$) online experiments were analysed to assess whether decision dynamics generalise across populations with differing variability and experimental control.
Across datasets, decision behaviour showed systematic dependencies on kinematic conditions, with increased reaction times (RTs) and choice variability in ambiguous situations. Longitudinal kinematics-based drift diffusion models (LK-DDMs) captured both decision proportions and reaction-time distributions in the narrow passage task and generalised across datasets with differing coverage of the experimental conditions, including lab and online data. The same accumulation framework transferred to a related decision-making task, indicating that the inferred dynamics are not task-specific. Incorporating visual looming in the drift function yielded selective improvements in short-distance Wait decisions, without global gains in reaction-time accuracy.
OSF link: https://osf.io/5d6em/overview?view_only=18580aa504f24d92a55cbccf53bb5deb
Assessing Human Drivers
From Raw Data to Context-Aware Interpretations
Initial research establishes the perspectives of driving examiners and professional truck drivers on the acceptance of data-driven tools to assess driver behavior. The work then demonstrates that practical methods using readily available GPS and accelerometer data can successfully identify driving styles and predict negative outcomes like fines and damage incidents at a population level. However, these simple metrics prove insufficient for fair individual assessment due to the lack of situational context embedded in such data.
To address this limitation, the thesis explores modern AI-based approaches. It demonstrates how AI systems from automated driving can provide continuous behavioral references to evaluate human performance, and concludes by showing that vision-language models can establish a more holistic, "context-aware" risk assessment using images of typical traffic situations. ...
Initial research establishes the perspectives of driving examiners and professional truck drivers on the acceptance of data-driven tools to assess driver behavior. The work then demonstrates that practical methods using readily available GPS and accelerometer data can successfully identify driving styles and predict negative outcomes like fines and damage incidents at a population level. However, these simple metrics prove insufficient for fair individual assessment due to the lack of situational context embedded in such data.
To address this limitation, the thesis explores modern AI-based approaches. It demonstrates how AI systems from automated driving can provide continuous behavioral references to evaluate human performance, and concludes by showing that vision-language models can establish a more holistic, "context-aware" risk assessment using images of typical traffic situations.
This dissertation aims to investigate the role of eye contact between drivers and pedestrians, as well as its influence on pedestrians’ road crossing intentions. Another aim of this dissertation is to assess the accuracy of eye-tracking devices and to objectively detect and operationalize driver-pedestrian eye contact using eye-tracking. Finally, this thesis aims to develop safety systems based on eye-tracking that can automatically analyze and contextualize gaze in traffic and warn vulnerable road users of danger. This thesis consists of four independently readable and empirical research papers.
The first study examines the effect of drivers’ eye contact on pedestrians’ crossing decisions using an online crowdsourced experiment. It shows that, although a car’s kinematics have a dominant effect, a driver’s eye contact also makes pedestrians feel safer and more likely to cross the road, and that the timing of the driver’s eye contact has an influence as well. The second study benchmarks the accuracies of mobile eye-trackers under static and dynamic conditions, finding that eccentricity worsens accuracy, but dynamicity does not necessarily worsen it. The third study presents a method to objectively detect and operationalize driver-pedestrian eye contact using two synchronized eye-trackers and computer vision, defining eye contact as mutual gaze within a 4° threshold. The fourth study explores the integration of mobile eye-tracking, object detection, and a vision-language model in an attempt to develop a real-time, context-aware safety system that can assess risk in traffic and enhance the situational awareness of road users.
This dissertation concludes that while eye contact is neither as powerful a cue as kinematics nor essential for crossing, it is still a “should-have” in driver-pedestrian interactions as it can increase perceived safety and willingness to cross. This thesis also concludes that certain types of external Human Machine Interfaces (eHMIs) – substitutes for the missing eye contact between pedestrians and automated vehicles – would be beneficial to maintain existing levels of comfort in interactions. Finally, this thesis also highlights the potential of using mobile eye-tracking in combination with computer vision and AI for applications in the traffic, manufacturing, medical, education, and other domains, and recommends topics for further research into eye contact and eye-tracking.
...
This dissertation aims to investigate the role of eye contact between drivers and pedestrians, as well as its influence on pedestrians’ road crossing intentions. Another aim of this dissertation is to assess the accuracy of eye-tracking devices and to objectively detect and operationalize driver-pedestrian eye contact using eye-tracking. Finally, this thesis aims to develop safety systems based on eye-tracking that can automatically analyze and contextualize gaze in traffic and warn vulnerable road users of danger. This thesis consists of four independently readable and empirical research papers.
The first study examines the effect of drivers’ eye contact on pedestrians’ crossing decisions using an online crowdsourced experiment. It shows that, although a car’s kinematics have a dominant effect, a driver’s eye contact also makes pedestrians feel safer and more likely to cross the road, and that the timing of the driver’s eye contact has an influence as well. The second study benchmarks the accuracies of mobile eye-trackers under static and dynamic conditions, finding that eccentricity worsens accuracy, but dynamicity does not necessarily worsen it. The third study presents a method to objectively detect and operationalize driver-pedestrian eye contact using two synchronized eye-trackers and computer vision, defining eye contact as mutual gaze within a 4° threshold. The fourth study explores the integration of mobile eye-tracking, object detection, and a vision-language model in an attempt to develop a real-time, context-aware safety system that can assess risk in traffic and enhance the situational awareness of road users.
This dissertation concludes that while eye contact is neither as powerful a cue as kinematics nor essential for crossing, it is still a “should-have” in driver-pedestrian interactions as it can increase perceived safety and willingness to cross. This thesis also concludes that certain types of external Human Machine Interfaces (eHMIs) – substitutes for the missing eye contact between pedestrians and automated vehicles – would be beneficial to maintain existing levels of comfort in interactions. Finally, this thesis also highlights the potential of using mobile eye-tracking in combination with computer vision and AI for applications in the traffic, manufacturing, medical, education, and other domains, and recommends topics for further research into eye contact and eye-tracking.
Background: Previous studies investigating the effects of AV2P communication have mostly been conducted through virtual reality (VR) providing researchers with safe experimentation methods and high experimental control, but also resulting in a common limitation: the lack of ecological validity and realism, thereby affecting participants’ behaviour and causing distractions. This study therefore introduces AR experiments that have been conducted in a real world environment to increase ecological validity.
Methods: An AR experiment was conducted in which 28 participants were situated in the real world with the objective to cross the road. The virtual vehicle, that was projected through a Varjo XR-3 head mounted display, approached from the right at a speed of 30 km/h while 4 interfaces (2x world-locked, head-locked, and vehicle-locked) appeared to communicate the vehicle’s intention towards the participants, in addition to a no-interface baseline. Participants were tasked with indicating when they were willing to cross through the push of a remote button from which their Willingness to cross and Decision certainty could be derived. Subjective data was collected after the trials and after the experiment through interviews and a questionnaire respectively.
Results: Results suggest a positive effect of the AV2P interfaces on the Willingness to cross and Decision certainty, although statistically not significant. In other words, Willingness to cross increases when the vehicle indicates that it will yield, and decreases when the vehicle communicates that it will not yield. Decision certainty also increases when an interface is present compared to the no-interface baseline. Moreover, participants indicated using the interfaces as a tool to validate their own decisions. Compared to the CAVE study, subjective intuitiveness ratings replicate in terms of observing higher intuitiveness of the interfaces than the no-interface baseline. However, the intuitiveness ratings were higher in the CAVE study than the real world AR experiment. Furthermore, the order of the top 3 most preferred interfaces ranking is in the opposite order. Both differences suggest that the increased ecological validity of the real world AR experiment introduces new insights into participants’ perception of interfaces. The Van der Laan acceptance scale shows that participants believe interfaces to be useful and satisfying overall.
Conclusion: The experiments suggest that AV2P interfaces have a positive effect on the crossing behaviour of pedestrians. Furthermore, participants indicate using the interfaces as a tool to validate their own decision, which increases confidence in their decisions. Although results partially replicate a previous virtual environment study, there are differences that suggest that real world AR experiments provide valuable insights into participants’ perception of interfaces in a more realistic experiment. ...
Background: Previous studies investigating the effects of AV2P communication have mostly been conducted through virtual reality (VR) providing researchers with safe experimentation methods and high experimental control, but also resulting in a common limitation: the lack of ecological validity and realism, thereby affecting participants’ behaviour and causing distractions. This study therefore introduces AR experiments that have been conducted in a real world environment to increase ecological validity.
Methods: An AR experiment was conducted in which 28 participants were situated in the real world with the objective to cross the road. The virtual vehicle, that was projected through a Varjo XR-3 head mounted display, approached from the right at a speed of 30 km/h while 4 interfaces (2x world-locked, head-locked, and vehicle-locked) appeared to communicate the vehicle’s intention towards the participants, in addition to a no-interface baseline. Participants were tasked with indicating when they were willing to cross through the push of a remote button from which their Willingness to cross and Decision certainty could be derived. Subjective data was collected after the trials and after the experiment through interviews and a questionnaire respectively.
Results: Results suggest a positive effect of the AV2P interfaces on the Willingness to cross and Decision certainty, although statistically not significant. In other words, Willingness to cross increases when the vehicle indicates that it will yield, and decreases when the vehicle communicates that it will not yield. Decision certainty also increases when an interface is present compared to the no-interface baseline. Moreover, participants indicated using the interfaces as a tool to validate their own decisions. Compared to the CAVE study, subjective intuitiveness ratings replicate in terms of observing higher intuitiveness of the interfaces than the no-interface baseline. However, the intuitiveness ratings were higher in the CAVE study than the real world AR experiment. Furthermore, the order of the top 3 most preferred interfaces ranking is in the opposite order. Both differences suggest that the increased ecological validity of the real world AR experiment introduces new insights into participants’ perception of interfaces. The Van der Laan acceptance scale shows that participants believe interfaces to be useful and satisfying overall.
Conclusion: The experiments suggest that AV2P interfaces have a positive effect on the crossing behaviour of pedestrians. Furthermore, participants indicate using the interfaces as a tool to validate their own decision, which increases confidence in their decisions. Although results partially replicate a previous virtual environment study, there are differences that suggest that real world AR experiments provide valuable insights into participants’ perception of interfaces in a more realistic experiment.
Save the meadow birds
Bird nest localization system for autonomous mowing machines
rendering parameters on user exploratory behaviour and perception during unconstrained exploration of artificial textures, aiming to discern a predominant tendency of interaction. Our results revealed, signal amplitude shapes human tactile
perception considerably during unconstrained exploration. We also observed, higher signal amplitudes were associated with lower finger scanning speeds, a trend tempered by significant individual differences, thereby affecting its practical effect. In contrast, the measured applied normal force and obtained finger movement pattern remained consistent and were not affected by different tactile rendering parameters. Notably, the rate of change of measured lateral force was found
to be a better metric for the perceived tactile dimensions than the lateral force magnitude. These findings enhance our understanding of perception and physics of such interactions, that could be vital for designing and delivering improved
haptic feedback on electrovibration-based tactile interfaces. ...
rendering parameters on user exploratory behaviour and perception during unconstrained exploration of artificial textures, aiming to discern a predominant tendency of interaction. Our results revealed, signal amplitude shapes human tactile
perception considerably during unconstrained exploration. We also observed, higher signal amplitudes were associated with lower finger scanning speeds, a trend tempered by significant individual differences, thereby affecting its practical effect. In contrast, the measured applied normal force and obtained finger movement pattern remained consistent and were not affected by different tactile rendering parameters. Notably, the rate of change of measured lateral force was found
to be a better metric for the perceived tactile dimensions than the lateral force magnitude. These findings enhance our understanding of perception and physics of such interactions, that could be vital for designing and delivering improved
haptic feedback on electrovibration-based tactile interfaces.
Towards continuous feedback on soft tissue anatomy during a percutaneous needle procedure in the liver
Exploring the use of endovascular markers to track the tumor location
An ex-vivo porcine liver with artificially created tumors and endovascular catheter markers was used. In the first experiment, robotic-assisted needle insertion was performed on seven tumors with a 13-gauge ablation needle. The second experiment involved simulating respiratory motion with an inflatable sachet to mimic the lungs and create a representable blow zone (the area affected by the inflated sachet). The displacement of the tumor- and endovascular catheter markers were tracked in the x-, y-, and z-directions using a C-arm system making Cone Beam Computed Tomography (CBCT). The x- and y-directions represents the horizontal plane within the liver, and the z-direction is the vertical plane (the direction of the ablation needle). The average offset in millimeters was calculated to quantify the error between the tumor- and catheter marker displacement.
The results of needle insertion showed that catheter markers placed 8-28 mm from the tumor could deduce tumor displacement in the x-direction, with a maximum offset of 1.23 mm. The catheter markers placed 8-13 mm from the tumor were also able to deduce displacement in the z-direction with a maximum offset of 0.23 mm and in Euclidean distance (total path length as measured using Pythagoras' theorem) with a maximum offset of 0.73 mm. Furthermore, the results indicated that, on average, catheter markers placed 8-28 mm from the tumor were able to accurately deduce tumor displacement for needle insertion depths of 0-15 mm. During respiratory motion simulation, tumor- and catheter marker displacement was influenced more by blow zone location than the distance between them. To apply these findings to the human body, it is recommended that the endovascular marker will be positioned in the same sagittal (longitudinal) and coronal (frontal) plane as the tumor. In this study, catheter markers could be used to deduce tumor displacement for inflation volumes of 0-500 ml, which is the typical resting breathing volume.
In conclusion, this study demonstrated that the ability to use endovascular catheter markers to deduce tumor displacement during a percutaneous needle procedure is influenced by the distance between the tumor- and the catheter marker, the depth of the needle, the inflation volume of simulated lungs, and whether the marker is positioned in the same sagittal and coronal plane in relation to the tumor. Future research should focus on determining the optimal number and location of endovascular markers, including a bigger variation and spread of tumor locations, and adjusting insertion techniques, to further realize the clinical applicability of endovascular catheter markers in percutaneous needle procedures. ...
An ex-vivo porcine liver with artificially created tumors and endovascular catheter markers was used. In the first experiment, robotic-assisted needle insertion was performed on seven tumors with a 13-gauge ablation needle. The second experiment involved simulating respiratory motion with an inflatable sachet to mimic the lungs and create a representable blow zone (the area affected by the inflated sachet). The displacement of the tumor- and endovascular catheter markers were tracked in the x-, y-, and z-directions using a C-arm system making Cone Beam Computed Tomography (CBCT). The x- and y-directions represents the horizontal plane within the liver, and the z-direction is the vertical plane (the direction of the ablation needle). The average offset in millimeters was calculated to quantify the error between the tumor- and catheter marker displacement.
The results of needle insertion showed that catheter markers placed 8-28 mm from the tumor could deduce tumor displacement in the x-direction, with a maximum offset of 1.23 mm. The catheter markers placed 8-13 mm from the tumor were also able to deduce displacement in the z-direction with a maximum offset of 0.23 mm and in Euclidean distance (total path length as measured using Pythagoras' theorem) with a maximum offset of 0.73 mm. Furthermore, the results indicated that, on average, catheter markers placed 8-28 mm from the tumor were able to accurately deduce tumor displacement for needle insertion depths of 0-15 mm. During respiratory motion simulation, tumor- and catheter marker displacement was influenced more by blow zone location than the distance between them. To apply these findings to the human body, it is recommended that the endovascular marker will be positioned in the same sagittal (longitudinal) and coronal (frontal) plane as the tumor. In this study, catheter markers could be used to deduce tumor displacement for inflation volumes of 0-500 ml, which is the typical resting breathing volume.
In conclusion, this study demonstrated that the ability to use endovascular catheter markers to deduce tumor displacement during a percutaneous needle procedure is influenced by the distance between the tumor- and the catheter marker, the depth of the needle, the inflation volume of simulated lungs, and whether the marker is positioned in the same sagittal and coronal plane in relation to the tumor. Future research should focus on determining the optimal number and location of endovascular markers, including a bigger variation and spread of tumor locations, and adjusting insertion techniques, to further realize the clinical applicability of endovascular catheter markers in percutaneous needle procedures.
Contactless Heat Measurement System for Retinal Coagulation
Design and Evaluation
Automotive Diminished Reality
A vulnerable road user study in a pedestrian crossing environment
Objective: In this thesis, we explore whether augmented and diminished reality interfaces, which, respectively, add and remove information from the environment, improve a pedestrian's feeling of road crossing safety, and how this information should be conveyed to the pedestrian.
Background: Literature shows that view occlusion is a prominent cause in pedestrian collisions. The research focus is currently on vehicle technology and pedestrian warning systems. Whether aiding pedestrians with camera views from unobstructed positions helps to overcome the view occlusion problem is unclear.
Methods: Twenty-eight participants engaged in a virtual reality urban road crossing scenario, in which they took on the role of a pedestrian. The pedestrian was situated on the curb and positioned such that the view on the road was largely obstructed. An autonomous vehicle approached and drove past from the left of the pedestrian. Through a head-mounted display, the participants experienced seven prototypes: baseline (i.e., no display), see-through display, transparent car, and both a head-locked and body-locked display with and without view guidance. The order in which participants encountered the prototypes was determined by a balanced Latin square, and each interface was tested by means of six trials with a non-yielding and a yielding scenario randomly selected such that in total three non-yielding and three yielding scenarios occurred in each block. The participants were instructed to continuously indicate whether they felt safe to cross by pressing a button. The interface's acceptance, workload and preference were measured with questionnaires.
Results: The participants' perceived feeling of safety revealed improved performance for all interfaces compared to the baseline condition. For the baseline condition, in which the vulnerable road user did not have access to occlusion-free information, the perceived feeling of safety was the lowest on average and decreased the earliest in the autonomous vehicle approaching phase, as well as scoring the lowest rating on acceptance. The see-through display and the transparent car interfaces, which used a combination of augmented and diminished reality properties to convey the information in a world-anchored manner to the pedestrians, achieved a higher acceptance and perceived feeling of safety than the head-locked and body-locked display interfaces.
Conclusion: A vulnerable road user's perceived feeling of safety can be increased by means of camera views from unobstructed positions to help overcome the view occlusion problem in common road crossing scenarios. This study's findings suggest a positive effect for diminished reality techniques for pedestrians, and future research could examine this technology further in more demanding scenarios. ...
Objective: In this thesis, we explore whether augmented and diminished reality interfaces, which, respectively, add and remove information from the environment, improve a pedestrian's feeling of road crossing safety, and how this information should be conveyed to the pedestrian.
Background: Literature shows that view occlusion is a prominent cause in pedestrian collisions. The research focus is currently on vehicle technology and pedestrian warning systems. Whether aiding pedestrians with camera views from unobstructed positions helps to overcome the view occlusion problem is unclear.
Methods: Twenty-eight participants engaged in a virtual reality urban road crossing scenario, in which they took on the role of a pedestrian. The pedestrian was situated on the curb and positioned such that the view on the road was largely obstructed. An autonomous vehicle approached and drove past from the left of the pedestrian. Through a head-mounted display, the participants experienced seven prototypes: baseline (i.e., no display), see-through display, transparent car, and both a head-locked and body-locked display with and without view guidance. The order in which participants encountered the prototypes was determined by a balanced Latin square, and each interface was tested by means of six trials with a non-yielding and a yielding scenario randomly selected such that in total three non-yielding and three yielding scenarios occurred in each block. The participants were instructed to continuously indicate whether they felt safe to cross by pressing a button. The interface's acceptance, workload and preference were measured with questionnaires.
Results: The participants' perceived feeling of safety revealed improved performance for all interfaces compared to the baseline condition. For the baseline condition, in which the vulnerable road user did not have access to occlusion-free information, the perceived feeling of safety was the lowest on average and decreased the earliest in the autonomous vehicle approaching phase, as well as scoring the lowest rating on acceptance. The see-through display and the transparent car interfaces, which used a combination of augmented and diminished reality properties to convey the information in a world-anchored manner to the pedestrians, achieved a higher acceptance and perceived feeling of safety than the head-locked and body-locked display interfaces.
Conclusion: A vulnerable road user's perceived feeling of safety can be increased by means of camera views from unobstructed positions to help overcome the view occlusion problem in common road crossing scenarios. This study's findings suggest a positive effect for diminished reality techniques for pedestrians, and future research could examine this technology further in more demanding scenarios.
Increased backing softness of planar smooth dry adhesives enhances contact area and frictional load capacity on a cylindrical substrate
With bio-inspired backings: Solid, Sponge & Inflatable
Design objectives for such a material (’backing’) were formulated and different types of bio-inspired backing concepts (solid, sponge, and inflatable) were fabricated. To gain insight in the suitability of these backing concepts with regard to some of the objectives, minimal required preload and minimal residual stresses to avoid detaching forces, two things are measured. Firstly, backing softness was measured as the compression stress-strain characteristic of the backing. Secondly, the preload contact stress distribution of backings was qualitatively measured.
The adhesive was a thin planar adhesive material reinforced with a planar mesh. One sponge backing type and one inflatable backing type were selected as practical backings to fabricate an adhesive system with. An experiment to measure frictional performance was done with these systems whereby backing softness was varied. These cuboid adhesive systems were pressed onto a cylindrical substrate and, after removal of the preload, loaded in the direction of the reinforcement while measuring frictional load capacity and contact area.
For both these two adhesive systems types, experiments showed that an increased backing softness caused an even or greater contact area throughout the whole loading cycle. The linear correlation coefficient, between rest phase contact area and maximum load capacity was 0.96, and at the end of the load phase, between the ’slide’ contact area and ’slide’ load capacity was 0.99.
With an inflatable or sponge backing design it is possible to make a softer backing compared to a solid design made by the same material. Only the sponge backing type distributed the preload relatively even at low and high compression, owing it to its stress plateau in its compression stress-strain characteristic. Although the inflatable has an equal pressure internally and also shows such a plateau, it was found that its contact stress is not even, due to the effect of its outer hull.
Concluding, the addition of a soft backing to help make and keep contact with a general shaped substrate, and thereby increasing load capacity, promises a new design paradigm in synthetic dry adhesives. Furthermore, the results indicates functional relevance of the presence of a relatively large and soft volume between the bones and the adhesive surface of the fingers/toe pads of geckos, tree frogs and humans. ...
Design objectives for such a material (’backing’) were formulated and different types of bio-inspired backing concepts (solid, sponge, and inflatable) were fabricated. To gain insight in the suitability of these backing concepts with regard to some of the objectives, minimal required preload and minimal residual stresses to avoid detaching forces, two things are measured. Firstly, backing softness was measured as the compression stress-strain characteristic of the backing. Secondly, the preload contact stress distribution of backings was qualitatively measured.
The adhesive was a thin planar adhesive material reinforced with a planar mesh. One sponge backing type and one inflatable backing type were selected as practical backings to fabricate an adhesive system with. An experiment to measure frictional performance was done with these systems whereby backing softness was varied. These cuboid adhesive systems were pressed onto a cylindrical substrate and, after removal of the preload, loaded in the direction of the reinforcement while measuring frictional load capacity and contact area.
For both these two adhesive systems types, experiments showed that an increased backing softness caused an even or greater contact area throughout the whole loading cycle. The linear correlation coefficient, between rest phase contact area and maximum load capacity was 0.96, and at the end of the load phase, between the ’slide’ contact area and ’slide’ load capacity was 0.99.
With an inflatable or sponge backing design it is possible to make a softer backing compared to a solid design made by the same material. Only the sponge backing type distributed the preload relatively even at low and high compression, owing it to its stress plateau in its compression stress-strain characteristic. Although the inflatable has an equal pressure internally and also shows such a plateau, it was found that its contact stress is not even, due to the effect of its outer hull.
Concluding, the addition of a soft backing to help make and keep contact with a general shaped substrate, and thereby increasing load capacity, promises a new design paradigm in synthetic dry adhesives. Furthermore, the results indicates functional relevance of the presence of a relatively large and soft volume between the bones and the adhesive surface of the fingers/toe pads of geckos, tree frogs and humans.
Indeed, more than 20% of highly myopic patients who have been treated for retinal diseases are subject to retinal detachment a few months after the surgery and are required to undergo a second surgery. It is believed that a membrane, also called Vitreous Cortex Remnants (VCR), that arises due to vitreoschisis,
a retinal disease, is the reason for the re-detachment. VCR is often not dealt with during surgery because its removal is time-costly, the VCR is not well visible and instruments are not optimally adapted for removing VCR. The work aims to develop and experimentally evaluate new methods of removing VCR. For that purpose, a series of test prototypes were manufactured, and three surgeons assessed the efficiency of the prototypes for removing VCR from dissected pig’s eyes. Each eye was treated pre-experimentally according to a new model that tries to recreate vitreoschisis in a young porcine eye. The efficiency of each test prototype was assessed based on the force that the instrument tip exerted on
the pig’s retina, the number of strokes taken to remove the VCR completely, the tissue damage and the time used. Furthermore, the optimal tip length was determined based on the surgeons’ feedback. The results show that the force greatly depended on the stiffness of the instrument tip and that the most efficient prototype consisted of a PVA wipe cut to size 6x1x1 mm and a 0.1 mm diameter Nitinol wire. The prototype exerted a maximum force of 0.68 gr. The number of strokes was around 40, and the optimal tip length was just under 4.5 mm. While the experiments showed that it is a promising design, the tip needs to be remodeled to comply with the low stiffness needed and to be able to fit within a 23 gauge tube. ...
Indeed, more than 20% of highly myopic patients who have been treated for retinal diseases are subject to retinal detachment a few months after the surgery and are required to undergo a second surgery. It is believed that a membrane, also called Vitreous Cortex Remnants (VCR), that arises due to vitreoschisis,
a retinal disease, is the reason for the re-detachment. VCR is often not dealt with during surgery because its removal is time-costly, the VCR is not well visible and instruments are not optimally adapted for removing VCR. The work aims to develop and experimentally evaluate new methods of removing VCR. For that purpose, a series of test prototypes were manufactured, and three surgeons assessed the efficiency of the prototypes for removing VCR from dissected pig’s eyes. Each eye was treated pre-experimentally according to a new model that tries to recreate vitreoschisis in a young porcine eye. The efficiency of each test prototype was assessed based on the force that the instrument tip exerted on
the pig’s retina, the number of strokes taken to remove the VCR completely, the tissue damage and the time used. Furthermore, the optimal tip length was determined based on the surgeons’ feedback. The results show that the force greatly depended on the stiffness of the instrument tip and that the most efficient prototype consisted of a PVA wipe cut to size 6x1x1 mm and a 0.1 mm diameter Nitinol wire. The prototype exerted a maximum force of 0.68 gr. The number of strokes was around 40, and the optimal tip length was just under 4.5 mm. While the experiments showed that it is a promising design, the tip needs to be remodeled to comply with the low stiffness needed and to be able to fit within a 23 gauge tube.
In this study, we developed and experimentally evaluated two ring-light configurations for intraocular illumination during vitreoretinal surgery: one for insertion through the pars plana (20 mm), and one for insertion through the cornea and placement in the posterior chamber (11 mm). Both prototypes are made from a 27 gauge Eckardt TwinLight (DORC, the Netherlands), placed inside a capillary tube cut in half through the length. Cuts were made in the fiber every 2 mm, perpendicular to the length of the fiber, to allow light to exit the fiber through the cladding.
By measuring the light intensity and illuminated area, we found that the ring-light configurations produce a lower light intensity but also a slightly larger illuminated area and a more diffuse and uniformly distributed illumination than the Eckardt TwinLight.
The placement of the ring-light in the posterior chamber proved to be unsafe and complex, since the installation procedure in ex-vivo porcine cadaver eyes could not be executed without damaging the lens bag, lens zonules, posterior iris and cornea, due to the lack of space in the posterior chamber, and the rigidity and sharp tip of the ring.
The ring-light configuration that is inserted through the pars plana also caused damage to the retina and lens bag, due to the ring’s rigidity and its sharp tip. However, this configuration shows potential when the ring would be made from a more flexible material and has an incorporated pigtail curve a the distal end, which can be easily achieved in a future version of the prototype. ...
In this study, we developed and experimentally evaluated two ring-light configurations for intraocular illumination during vitreoretinal surgery: one for insertion through the pars plana (20 mm), and one for insertion through the cornea and placement in the posterior chamber (11 mm). Both prototypes are made from a 27 gauge Eckardt TwinLight (DORC, the Netherlands), placed inside a capillary tube cut in half through the length. Cuts were made in the fiber every 2 mm, perpendicular to the length of the fiber, to allow light to exit the fiber through the cladding.
By measuring the light intensity and illuminated area, we found that the ring-light configurations produce a lower light intensity but also a slightly larger illuminated area and a more diffuse and uniformly distributed illumination than the Eckardt TwinLight.
The placement of the ring-light in the posterior chamber proved to be unsafe and complex, since the installation procedure in ex-vivo porcine cadaver eyes could not be executed without damaging the lens bag, lens zonules, posterior iris and cornea, due to the lack of space in the posterior chamber, and the rigidity and sharp tip of the ring.
The ring-light configuration that is inserted through the pars plana also caused damage to the retina and lens bag, due to the ring’s rigidity and its sharp tip. However, this configuration shows potential when the ring would be made from a more flexible material and has an incorporated pigtail curve a the distal end, which can be easily achieved in a future version of the prototype.
The present study investigated whether social pressure truly changes food experience by means of explicit and implicit measures of food liking. Explicit ratings were EmojiGrid valence and arousal ratings in response to familiar and unfamiliar food images and soups. Implicit measures consisted of frontal alpha asymmetry during pre-selected scenes of a movie about Japanese soy sauce as well as sip size of the soup. Explicit and implicit measures were compared to assess the effect of social pressure on Japanese and Dutch food liking.
No differences between the social pressure (n = 19) and control group (n = 23) emerged in any of the measures. Explicit ratings and the implicit measure sip size, but not frontal alpha asymmetry during watching the movie, showed differences between participants with high and low food neophobia. The insensitivity of frontal alpha asymmetry to food neophobia groups could be explained by the movie scenes showing rather familiar foods. BMI grouping similarly showed no effect on frontal alpha asymmetry during watching the movie, but also explicit measures were unaffected.
It was concluded that the social pressure intervention itself was not effective in inducing increased liking of Japanese food, since there was no increase in neither reported liking nor ‘true’ liking. Additional ways to induce social pressure, e.g., observation during rating, are advisable if the study was repeated. Furthermore, the use of stronger stimuli to induce approach or avoidance motivation as measured by frontal alpha asymmetry, is recommended. It cannot be concluded whether social pressure truly affects food experience. ...
The present study investigated whether social pressure truly changes food experience by means of explicit and implicit measures of food liking. Explicit ratings were EmojiGrid valence and arousal ratings in response to familiar and unfamiliar food images and soups. Implicit measures consisted of frontal alpha asymmetry during pre-selected scenes of a movie about Japanese soy sauce as well as sip size of the soup. Explicit and implicit measures were compared to assess the effect of social pressure on Japanese and Dutch food liking.
No differences between the social pressure (n = 19) and control group (n = 23) emerged in any of the measures. Explicit ratings and the implicit measure sip size, but not frontal alpha asymmetry during watching the movie, showed differences between participants with high and low food neophobia. The insensitivity of frontal alpha asymmetry to food neophobia groups could be explained by the movie scenes showing rather familiar foods. BMI grouping similarly showed no effect on frontal alpha asymmetry during watching the movie, but also explicit measures were unaffected.
It was concluded that the social pressure intervention itself was not effective in inducing increased liking of Japanese food, since there was no increase in neither reported liking nor ‘true’ liking. Additional ways to induce social pressure, e.g., observation during rating, are advisable if the study was repeated. Furthermore, the use of stronger stimuli to induce approach or avoidance motivation as measured by frontal alpha asymmetry, is recommended. It cannot be concluded whether social pressure truly affects food experience.
Preventing Anastomotic Leakage
An experimental approach to the redesign of a colorectal stent
This thesis focuses on the redesign of this stent to cover an anastomosis. Two main problems with the stent were stent migration due to insufficient friction between the stent and the colonic wall, and intestinal blockage due to the presence of the stent.
Preliminary research and a literature study showed that the addition of barbs to the stent could increase friction with the colonic wall. Optimal barb dimensions were researched on fresh colon specimens in an experimental setup. Ideal barb parameters were a height of 1.5 mm, diameter of 1.0 mm, an angle of 30 degrees, with a distribution of 3 barbs per cm2. In addition, the ideal stent diameter was explored in an experiment with fresh colon specimens. The stent should expand the colon with 50-60%. To safely insert and extract a stent with barbs in the colon, a patent search was executed to explore the possibilities of barb and colon protection. A stent with a reducible diameter and a tubular protection structure were identified as the most promising methods to safely insert a barbed stent. The second problem of intestinal blockage was analyzed and causes of intestinal blockage were identified. Minimizing the frontal contact surface at the proximal end of the stent was assumed to be the most important factor to reduce intestinal blockage. A minimal frontal contact surface also reduces the force that feces exerts on the stent, thus reducing the chance of stent migration.
The previously mentioned experiments and analysis formed the basis of a list of design requirements for a new prototype stent. The requirements were divided into five categories; fixation, dimensions, materials, delivery method and performance. After analyzing different manufacturing processes and available materials, two concepts were designed and produced. One concept was chosen after careful considerations of both options.
The final prototype consisted of a stent with barbs that was 3D printed. This design was validated on the set of requirements that were set up earlier. The material of the stent is both flexible and stiff. For insertion and extraction of the stent, the diameter can be reduced by longitudinal inward folding, while the stent forms a rigid tube while in a deployed state. The barbs are stiff and strong and can withstand the force that would move the stent. The frontal contact surface of the stent was reduced by more than 18 times compared to the old prototype, to reduce the influence on intestinal blockage. The stent is surrounded by a sheet to protect the barbs and prevent tissue damage during insertion. A validation experiment showed that the stent was improved in fixation compared to the old prototype. Therefore, based on the research executed in this thesis, the final prototype should theoretically migrate less and cause less blockage. However, an ex-vivo experiment should validate the fixation force of the new prototype, and in-vivo experiments on pigs should determine if the prototype actually does not migrate and actually does not cause intestinal blockage. ...
This thesis focuses on the redesign of this stent to cover an anastomosis. Two main problems with the stent were stent migration due to insufficient friction between the stent and the colonic wall, and intestinal blockage due to the presence of the stent.
Preliminary research and a literature study showed that the addition of barbs to the stent could increase friction with the colonic wall. Optimal barb dimensions were researched on fresh colon specimens in an experimental setup. Ideal barb parameters were a height of 1.5 mm, diameter of 1.0 mm, an angle of 30 degrees, with a distribution of 3 barbs per cm2. In addition, the ideal stent diameter was explored in an experiment with fresh colon specimens. The stent should expand the colon with 50-60%. To safely insert and extract a stent with barbs in the colon, a patent search was executed to explore the possibilities of barb and colon protection. A stent with a reducible diameter and a tubular protection structure were identified as the most promising methods to safely insert a barbed stent. The second problem of intestinal blockage was analyzed and causes of intestinal blockage were identified. Minimizing the frontal contact surface at the proximal end of the stent was assumed to be the most important factor to reduce intestinal blockage. A minimal frontal contact surface also reduces the force that feces exerts on the stent, thus reducing the chance of stent migration.
The previously mentioned experiments and analysis formed the basis of a list of design requirements for a new prototype stent. The requirements were divided into five categories; fixation, dimensions, materials, delivery method and performance. After analyzing different manufacturing processes and available materials, two concepts were designed and produced. One concept was chosen after careful considerations of both options.
The final prototype consisted of a stent with barbs that was 3D printed. This design was validated on the set of requirements that were set up earlier. The material of the stent is both flexible and stiff. For insertion and extraction of the stent, the diameter can be reduced by longitudinal inward folding, while the stent forms a rigid tube while in a deployed state. The barbs are stiff and strong and can withstand the force that would move the stent. The frontal contact surface of the stent was reduced by more than 18 times compared to the old prototype, to reduce the influence on intestinal blockage. The stent is surrounded by a sheet to protect the barbs and prevent tissue damage during insertion. A validation experiment showed that the stent was improved in fixation compared to the old prototype. Therefore, based on the research executed in this thesis, the final prototype should theoretically migrate less and cause less blockage. However, an ex-vivo experiment should validate the fixation force of the new prototype, and in-vivo experiments on pigs should determine if the prototype actually does not migrate and actually does not cause intestinal blockage.
Stability in Truck Driving Behaviour
A Geo-Specific Analysis
The current thesis extends the geo-specific analysis of (truck) driving data by analysing stability in truck driving behaviour with a focus on time and location (urban areas and motorways). Here correlation analysis has been used to explore stability. Correlational analysis elucidates that metrics such as the number of headway warnings, braking events and lane departure warnings are stable over space and time. A discussion reflects on the role of vehicle characteristics (i.e. mass and engine power) towards stability.
It is concluded that in the case of spatial stability: Mean point speed has higher stability on motorways than in urban areas. It has been determined that trucks with higher mass and lower engine power tend to have lower mean speed than the norm. Contrary to mean point speed, headway warnings show higher stability in urban areas than on motorways. Braking events and lane departure warnings exhibit high stability. Secondly, a strong correlation between (t and t+1) hours over the entire day is observed for temporal stability.
This research is a precursor to building generalised models for profiling drivers and assessing various driving patterns. An in-depth understanding of different driving patterns can help driver coaching companies better understand metrics when time and location are factored in before providing targeted feedback. Apart from this can also facilitate fleet management. The code for analysing this dataset is accessible online and may stimulate future researchers to explore this dataset further. ...
The current thesis extends the geo-specific analysis of (truck) driving data by analysing stability in truck driving behaviour with a focus on time and location (urban areas and motorways). Here correlation analysis has been used to explore stability. Correlational analysis elucidates that metrics such as the number of headway warnings, braking events and lane departure warnings are stable over space and time. A discussion reflects on the role of vehicle characteristics (i.e. mass and engine power) towards stability.
It is concluded that in the case of spatial stability: Mean point speed has higher stability on motorways than in urban areas. It has been determined that trucks with higher mass and lower engine power tend to have lower mean speed than the norm. Contrary to mean point speed, headway warnings show higher stability in urban areas than on motorways. Braking events and lane departure warnings exhibit high stability. Secondly, a strong correlation between (t and t+1) hours over the entire day is observed for temporal stability.
This research is a precursor to building generalised models for profiling drivers and assessing various driving patterns. An in-depth understanding of different driving patterns can help driver coaching companies better understand metrics when time and location are factored in before providing targeted feedback. Apart from this can also facilitate fleet management. The code for analysing this dataset is accessible online and may stimulate future researchers to explore this dataset further.