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N.N.M. Rozsa

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10 records found

Doctoral thesis (2025) - N.N.M. Rozsa, M.A.P. Pertijs, M.D. Verweij
Accurately estimating the risk of Abdominal Aortic Aneurysm (AAA) rupture is key to improving the treatment of patients suffering from this disease. While conventional risk assessment is based on the geometrical properties of the vessel, acquired via ultrasound imaging, it is expected that acquiring data on more of the vessel's properties will lead to an improved prediction of the risk of rupture, and thus improved treatment of patients. These properties include 3-dimensional (3-D) blood flow through the vessel and its 3-D elasticity, which require an ultrasound probe consisting of thousands of transducer elements capable of imaging a large volume at very high volume-rates. To address this challenge, this dissertation presents the design, fabrication and characterization of a 4096-element ultrasound probe for high-volume-rate (HVR) cardiovascular imaging.

The probe consists of two custom-designed application-specific integrated circuits (ASICs), each of which interfaces with a 2048-element transducer array, which in turn can consist of bulk-fabricated piezo-electric transducers, or monolithically integrated capacitive micro-machined ultrasound transducers (CMUTs). The probe can image a 60◦×60◦×10-cm volume at 2000 volumes/s, the highest volume-rate with in-probe channel-count reduction reported to date. It uses a 2×2 delay-and-sum micro-beamformer (µBF) and 2× time-division multiplexing (TDM) to achieve an 8× receive (RX) channel count reduction, and is the first to scale this combination of techniques to an array of thousands of elements. Equalization, trained using a pseudorandom bit-sequence generated on the chip, reduces TDM-induced crosstalk by 10 dB, enabling power-efficient scaling of the cable drivers. The ASICs also implement a novel transmit (TX) beamformer (BF) that operates as a programmable digital pipeline, which enables steering of arbitrary pulse-density modulated waveforms. The TX BF drives element-level 65 V unipolar pulsers, which in turn drive the transducer elements. Both the TX BF and RX µBF are programmed with shift-registers that can either be programmed in a row-column fashion for fast upload.

As the ASICs in the probe can accommodate multiple transducer technologies, two variants of the probe were developed and acoustically validated to compare the performance of a CMUT and bulk PZT transducer array, demonstrating the potential of using the probe as a prototyping platform for further research activities, enabling validation of ultrasound arrays of up to thousands of elements. The CMUT variant probe was also used to characterize and compare the performance of multiple imaging schemes for the intended application. The scheme for imaging a 60◦×60◦×10-cm volume at 2000 volumes/s with half of the array achieves a median resolution of 4.0◦x1.9◦x660 µm, which accurately matches simulation results. Using this imaging scheme, Doppler images were reconstructed without aliasing artefacts of a blood-mimicking fluid flowing through a flow phantom with an average velocity up to 400 mm/s, which represents the peak velocity of blood in AAAs. Overall, the dissertation demonstrates that the developed system is a promising solution for ultrasound research and the improved treatment of AAAs.
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Journal article (2025) - Nikola Radeljic-Jakic, Adriaan J. Flikweert, Nuriel N.M. Rozsa, Hendrik J. Vos, Michiel A.P. Pertijs
Emerging handheld and wearable ultrasound devices enable diagnosis and long-term monitoring outside clinical settings. They require a low-power, highly complex, locally integrated system to process the RF data. The analog-to-digital converter (ADC) is a critical building block in the receive chain of these systems as it enables digital beamforming and image reconstruction. However, the ADCs currently used in cart-based imaging systems are bulky and consume too much power to be integrated into battery-powered devices. This article investigates how the area and power consumption of the commonly used successive approximation register (SAR) ADC can be reduced without negatively affecting B-mode and color-Doppler image quality. A Monte Carlo (MC) simulation study was performed in which RF data acquired with a phased-array transducer in Field II were digitized using a model of a nonideal ADC. Five different nonidealities were applied to four commonly used SAR-ADC architectures. B-mode and color-Doppler images were reconstructed from the digitized RF data. The impact of the nonidealities on the image quality was evaluated by means of three image quality metrics (IQM): peak signal-to-noise ratio (PSNR), structural similarity index (SSIM), and contrast-to-noise ratio (CNR). The effectiveness of error correction and ways of calibration are also discussed. The results show that both B-mode imaging and color-Doppler imaging are inherently resilient to nonidealities, particularly capacitor mismatch, leading to relaxed ADC requirements and paving the way for more practical in-probe digitization. ...
This article presents a 4096-element ultrasound probe for high volume-rate (HVR) cardiovascular imaging. The probe consists of two application-specific integrated circuits (ASICs), each of which interfaces with a 2048-element monolithically-integrated capacitive micro-machined ultrasound transducer (CMUT) array. The probe can image a 60° × 60° × 10-cm volume at 2000 volumes/s, the highest volume-rate with in-probe channel-count reduction reported to date. It uses 2 × 2 delay-and-sum micro-beamforming (μBF) and 2× time-division multiplexing (TDM) to achieve an 8× receive (RX) channel-count reduction. Equalization, trained using a pseudorandom bit-sequence generated on the chip, reduces TDM-induced crosstalk by 10 dB, enabling power-efficient scaling of the cable drivers. The ASICs also implement a novel transmit (TX) beamformer (BF) that operates as a programmable digital pipeline, which enables steering of arbitrary pulse-density modulated (PDM) waveforms. The TX BF drives element-level 65 V unipolar pulsers, which in turn drive the CMUT array. Both the TX BF and RX μBF are programmed with shift-registers (SRs) that can either be programmed in a row-column fashion for fast upload times, or daisy-chain fashion for a higher flexibility. The layout of the ASICs is matched to the 365-μm-pitch monolithically-integrated CMUT array. While operating, the RX and logic power consumption per element is 0.85 and 0.10 mW, respectively. TX power consumption is highly waveform dependent, but is nominally 0.34 mW. Compared to the prior art, the probe has the highest volume rate, and features among the largest imaging arrays (both in terms of element-count and aperture) with a high flexibility in defining the TX waveform. These properties make it a suitable option for applications requiring HVR imaging of a large region of interest. ...
24096-Element CMUT Array" (IEEE Journal of Solid-State Circuits (2025) 60:4 (1397-1410) DOI: 10.1109/JSSC.2025.3534087)">
IN [1], there is a mistake in the timing diagram shown in Fig. 6. Switches S 1-S 4 are skipping some of the samples and the rate at which they are operating implies a TDM rate of 10 MHz, whereas (as described in [1]) this should be 20 MHz. In the updated Fig. 6, S 1-S 4 have been updated and a minor change has been made to the timing shown for switches Q1 and Q2, such that the correct TDM rate is indicated and no sample provided to the S/H stage via N1-N4 is skipped in the diagram. (Figure presented). ...
This article presents an application-specific integrated circuit (ASIC) for battery-powered ultrasound (US) devices. The ASIC implements a novel energy-efficient high-voltage (HV) pulser that generates HV transmit (TX) pulses directly from a low-voltage (LV) battery supply. By means of a single off-chip inductor, energy is supplied to a US transducer in a resonant fashion, directly generating half-period sinusoidal HV pulses on the transducer, while consuming substantially less energy than a conventional class-D pulser. By recycling residual reactive energy from the transducer back to the input, the energy consumption is further reduced by more than 50%. The autocalibration techniques are leveraged to deal with tolerances of the inductor, transducer, and battery supply and thus maximize the energy efficiency. A prototype chip was fabricated in TSMC 0.18-μm HV BCD technology and used to drive external 120-pF capacitive micromachined US transducers (CMUTs) with a center frequency of approximately 2.5 MHz. Electrical measurements show that the prototype can generate pulses with a peak amplitude between 10 and 30 V accurate to within ±1 V. Acoustic measurements demonstrate successful ultrasonic pulse transmission and pulse-echo measurements. The prototype reaches a peak efficiency of 0.23 fCV 2 , which is the highest reported to date for HV pulsers targeting US imaging. ...
Poster (2023) - N. Radeljic-Jakic, A. Flikweert, Y. Hopf, N. Rozsa, M. Pertijs
In traditional 2-D ultrasound probes, a 1-D transducer array is directly connected to an imaging system. With the introduction of 3-D probes that have 2-D arrays with thousands of elements, this approach has become impractical. Ultrasound ASICs can enable this transition by shifting part of the system functionality into the probe to reduce interconnect and cost. On-chip implementation of the analog-to-digital converter (ADC) has recently been shown to be particularly beneficial but comes with a significant power and area penalty. Current ultrasound converters are commonly implemented as successive approximation register (SAR) ADCs and designed following general-purpose design methodologies. In this work, the impact of SAR ADC non-idealities on postprocessed images is studied to achieve better trade-offs between performance and cost for ultrasound imaging. ...
High frame rate three-dimensional (3D) ultrasound imaging would offer excellent possibilities for the accurate assessment of carotid artery diseases. This calls for a matrix transducer with a large aperture and a vast number of elements. Such a matrix transducer should be interfaced with an application-specific integrated circuit (ASIC) for channel reduction. However, the fabrication of such a transducer integrated with one very large ASIC is very challenging and expensive. In this study, we develop a prototype matrix transducer mounted on top of multiple identical ASICs in a tiled configuration. The matrix was designed to have 7680 piezoelectric elements with a pitch of 300 μm × 150 μm integrated with an array of 8 × 1 tiled ASICs. The performance of the prototype is characterized by a series of measurements. The transducer exhibits a uniform behavior with the majority of the elements working within the −6 dB sensitivity range. In transmit, the individual elements show a center frequency of 7.5 MHz, a −6 dB bandwidth of 45%, and a transmit efficiency of 30 Pa/V at 200 mm. In receive, the dynamic range is 81 dB, and the minimum detectable pressure is 60 Pa per element. To demonstrate the imaging capabilities, we acquired 3D images using a commercial wire phantom. ...
Journal article (2022) - Huajun Zhang, Nuriel N.M. Rozsa, Marco Berkhout, Qinwen Fan
The power supply rejection ratio (PSRR) of conventional differential closed-loop Class-D amplifiers is limited by the feedback and input resistor mismatch and finite common-mode rejection ratio (CMRR) of the operational transconductance amplifier (OTA) in the first integrator. This article presents a 14.4-V Class-D amplifier employing chopping to tackle the mismatch, thereby improving the PSRR. However, chopping-induced intermodulation (IM) within a pulsewidth modulation (PWM)-based Class-D amplifier can severely degrade PSRR and linearity. Techniques to mitigate such IM are proposed and analyzed. To chop the 14.4-V PWM output signal, a high-voltage (HV) chopper employing double-diffused MOS (DMOS) transistors is developed. Its timing is carefully aligned with that of the low-voltage (LV) choppers to avoid further linearity degradation. The prototype, fabricated in a 180-nm BCD process, achieves a PSRR of >110 dB at low frequencies, which remains above 79 dB up to 20 kHz. It achieves a total harmonic distortion (THD) of -109.1 dB and can deliver a maximum of 14 W into an 8- \Omega load with 93% efficiency while occupying a silicon area of 5 mm2. ...
Conference paper (2022) - Djalma Simoes Dos Santos, Fabian Fool, Taehoon Kim, Emile Noothout, Nuriel Rozsa, Hendrik J. Vos, Johan G. Bosch, Michiel A.P. Pertijs, Martin D. Verweij, Nico De Jona
Over the past decades, ultrasound imaging has made considerable progress based on the advancement of imaging systems as well as transducer technology. With the need for advanced transducer arrays with complex designs and technical requirements, there is also a need for suitable tools to characterize such transducers. However, despite the importance of acoustic characterization to assess the performance of novel transducer arrays, the characterization process of highly complex transducers might involve various manual steps, which are laborious, time-consuming, and subject to errors. These factors can hinder the full characterization of a prototype transducer, leading to an under-representation or inadequate evaluation. To come to an extensive, high-quality evaluation of a prototype transducer, the acoustic characterization of each transducer element is indispensable in both transmit and receive operations. In this paper, we propose a pipeline to automatically perform the acoustic characterization of a matrix transducer using a research imaging system. The performance of the pipeline is tested on a prototype matrix transducer consisting of 960 elements. The results show that the proposed pipeline is capable of performing the complete acoustic characterization of a high-element count transducer in a fast and convenient way. ...
Conference paper (2021) - Huajun Zhang, Nuriel Rozsa, Marco Berkhout, Qinwen Fan
This paper reports a chopper Class-D audio amplifier that obtains high PSRR over the entire audio band. A chopping scheme is proposed to minimize intermodulation distortion between pulse-width modulation (PWM) and chopping in the audio band. A high-voltage chopper is developed to handle a 14.4 V PWM signal. Timing matching techniques are proposed to minimize chopping nonidealities which ensure good PSRR and THD. Fabricated in a 180nm BCD process, the prototype obtains a PSRR >109 dB at 217 Hz and >83.7 dB over the entire audio band. It also achieves -109.1 dB/-98 dB THD/THD+N and can deliver a maximum of 13 W to an 8-Ω load. ...