L. Marchal Crespo
Please Note
31 records found
1
Personalization of functional electrical stimulation (FES) patterns for cycling
An application on rehabilitation of incomplete spinal cord injury (iSCI) patients
Objective: The goal of this work is to first develop a methodology for the creation of FES patterns from electromyography (EMG), specifically from muscle synergy analysis. Then, to study how the obtained patterns compare to a standard one. We hypothesized that (1) the standard FES pattern would diverge from healthy muscle-activation timing, (2) it was designed for intermediate cadences, and (3) synergy-based patterns would yield smoother pedaling and better user ratings.
Methods: During data acquisition, we recorded EMG of eight leg muscles from eight healthy controls and two SCI patients while cycling at 30, 50, and 70 revolutions per minute (rpm) on a recumbent ergometer. Non-negative matrix factorization extracted muscle synergies and reconstructed EMG envelopes, which defined personalized stimulation ranges and amplitude profiles for each muscle. We quantified inter-limb symmetry and deviations of the personalized pattern from the standard one to characterize how each FES parameter set differed across trials. In the evaluation phase, eight healthy participants tested three patterns in random order for six minutes: the standard pattern, a fixed-50-rpm synergy-based pattern, and a synergy-based pattern adapting to the real-time cadence. Outcome measures were rpm variability and user perception ratings.
Results: Two of our three hypotheses were confirmed: (1) the standard FES pattern diverged significantly from healthy muscle-activation timing, and (2) it appeared to have been indeed designed for mid-range cadences (50 rpm approx.). However, the synergy-based personalization did not yield clear improvements over the standard pattern, and subjective preferences did not consistently align with objective metrics. Since the statistical tests yielded no significant difference between trials, two illustrative cases were shown, highlighting variability.
Conclusion: A practical workflow is recommended to first generate candidate patterns from muscle synergy analysis, conduct brief comparative trials using application-specific measures and user feedback, and then select the pattern that best balances these criteria for the intended rehabilitation protocol. ...
Objective: The goal of this work is to first develop a methodology for the creation of FES patterns from electromyography (EMG), specifically from muscle synergy analysis. Then, to study how the obtained patterns compare to a standard one. We hypothesized that (1) the standard FES pattern would diverge from healthy muscle-activation timing, (2) it was designed for intermediate cadences, and (3) synergy-based patterns would yield smoother pedaling and better user ratings.
Methods: During data acquisition, we recorded EMG of eight leg muscles from eight healthy controls and two SCI patients while cycling at 30, 50, and 70 revolutions per minute (rpm) on a recumbent ergometer. Non-negative matrix factorization extracted muscle synergies and reconstructed EMG envelopes, which defined personalized stimulation ranges and amplitude profiles for each muscle. We quantified inter-limb symmetry and deviations of the personalized pattern from the standard one to characterize how each FES parameter set differed across trials. In the evaluation phase, eight healthy participants tested three patterns in random order for six minutes: the standard pattern, a fixed-50-rpm synergy-based pattern, and a synergy-based pattern adapting to the real-time cadence. Outcome measures were rpm variability and user perception ratings.
Results: Two of our three hypotheses were confirmed: (1) the standard FES pattern diverged significantly from healthy muscle-activation timing, and (2) it appeared to have been indeed designed for mid-range cadences (50 rpm approx.). However, the synergy-based personalization did not yield clear improvements over the standard pattern, and subjective preferences did not consistently align with objective metrics. Since the statistical tests yielded no significant difference between trials, two illustrative cases were shown, highlighting variability.
Conclusion: A practical workflow is recommended to first generate candidate patterns from muscle synergy analysis, conduct brief comparative trials using application-specific measures and user feedback, and then select the pattern that best balances these criteria for the intended rehabilitation protocol.
Methods aEEG recordings from neurologically healthy neonates between 32 and 42 weeks postmenstrual age (PMA) were annotated for quiet sleep (QS) and non-quiet sleep (NQS) by a single expert clinician.
Results Five classifiers were trained to classify QS and NQS. A k-nearest neighbors model achieved a mean Cohen’s Kappa of 0.71± 0.12 in preterm infants, decreasing to 0.48 ± 0.21 in term infants. Features from QS segments were strongly correlated with PMA, enabling a PMA predictor model to achieve an average error of 0.88 weeks.
Conclusion Although performance on QS/NQS classification was strong for neonates between 33 and 37 weeks PMA, generalization across the full 32–42 week range remains challenging. Nevertheless, the low average error of the PMA predictor highlights its potential as a tool for detecting mild neuromaturation delays.
...
Methods aEEG recordings from neurologically healthy neonates between 32 and 42 weeks postmenstrual age (PMA) were annotated for quiet sleep (QS) and non-quiet sleep (NQS) by a single expert clinician.
Results Five classifiers were trained to classify QS and NQS. A k-nearest neighbors model achieved a mean Cohen’s Kappa of 0.71± 0.12 in preterm infants, decreasing to 0.48 ± 0.21 in term infants. Features from QS segments were strongly correlated with PMA, enabling a PMA predictor model to achieve an average error of 0.88 weeks.
Conclusion Although performance on QS/NQS classification was strong for neonates between 33 and 37 weeks PMA, generalization across the full 32–42 week range remains challenging. Nevertheless, the low average error of the PMA predictor highlights its potential as a tool for detecting mild neuromaturation delays.
Assessing an Augmented Reality Surgical Simulator
A Comparative Study of Productive Failure and Productive Success for Novice Motor Skill Learning
We focused on creating a preliminary framework that provides haptic feedback on the altitudinal axis of the quadcopter to the pilot using the control method Model Predictive Control (MPC). The haptic feedback is provided on the z-axis of a haptic Sigma.7 robot, which is also used as a remote controller to fly the quadcopter. The MPC implements the dynamical models of the quadcopter, and a haptic Sigma.7 robot, to determine the minimal force required to steer the Sigma.7 robot towards motor task completion. The system should provide minimal haptic force feedback within the proposed design requirements to prevent reliance on the assistance. We evaluated the effectiveness of our framework by evaluating its ability to control the quadcopter to the desired altitude setpoint under autonomous conditions using a haptic Sigma robot. Additionally, the design and performance of each of the individual building blocks of this framework, i.e. the quadcopter model, the haptic interface, and the MPC, were evaluated separately. The quadcopter, with the implementation of the onboard PID controllers, eliminating the steady-state errors and meeting the required settling times. The Sigma.7 model was sufficient within the established time horizon and range of operation, although shows limitations due to unmodelled frictional forces. The completed framework is capable of providing the Sigma.7 with the necessary input command to autonomously guide the quadcopter to its desired references in real-time, therefore completing its primary objective. Future work should explore improving the model components and integrating human elements into the predictive model. ...
We focused on creating a preliminary framework that provides haptic feedback on the altitudinal axis of the quadcopter to the pilot using the control method Model Predictive Control (MPC). The haptic feedback is provided on the z-axis of a haptic Sigma.7 robot, which is also used as a remote controller to fly the quadcopter. The MPC implements the dynamical models of the quadcopter, and a haptic Sigma.7 robot, to determine the minimal force required to steer the Sigma.7 robot towards motor task completion. The system should provide minimal haptic force feedback within the proposed design requirements to prevent reliance on the assistance. We evaluated the effectiveness of our framework by evaluating its ability to control the quadcopter to the desired altitude setpoint under autonomous conditions using a haptic Sigma robot. Additionally, the design and performance of each of the individual building blocks of this framework, i.e. the quadcopter model, the haptic interface, and the MPC, were evaluated separately. The quadcopter, with the implementation of the onboard PID controllers, eliminating the steady-state errors and meeting the required settling times. The Sigma.7 model was sufficient within the established time horizon and range of operation, although shows limitations due to unmodelled frictional forces. The completed framework is capable of providing the Sigma.7 with the necessary input command to autonomously guide the quadcopter to its desired references in real-time, therefore completing its primary objective. Future work should explore improving the model components and integrating human elements into the predictive model.
The experiment involved participants performing seated lateral leaning tasks where they were instructed to touch virtual goals with their heads. During some trials, the avatar unexpectedly deviated from the user's intended motion.
The results revealed that contrary to expectations, the avatar follower effect did not occur. Instead, an opposing effect was observed where participants' motions contradicted the avatar's deviations, particularly when the avatar stopped prior to the instructed goal. This effect was not influenced by the user's perspective (first or third person) or the scoring mechanism used in the game. However, individual personality traits, such as a tendency for autonomy or a focus on rewards, did affect the strength of the opposing effect.
These findings suggest that using avatar deviations to guide upper body and head motion in VR may not be effective, thus unsuited for applications such as motion sickness prevention in automated vehicles. ...
The experiment involved participants performing seated lateral leaning tasks where they were instructed to touch virtual goals with their heads. During some trials, the avatar unexpectedly deviated from the user's intended motion.
The results revealed that contrary to expectations, the avatar follower effect did not occur. Instead, an opposing effect was observed where participants' motions contradicted the avatar's deviations, particularly when the avatar stopped prior to the instructed goal. This effect was not influenced by the user's perspective (first or third person) or the scoring mechanism used in the game. However, individual personality traits, such as a tendency for autonomy or a focus on rewards, did affect the strength of the opposing effect.
These findings suggest that using avatar deviations to guide upper body and head motion in VR may not be effective, thus unsuited for applications such as motion sickness prevention in automated vehicles.
Implicit Visual Feedback Distortions in Gait Rehabilitation Using Virtual Reality
Visual Feedback Distortion from Virtual Reality Avatars Does not Result in Effects on Gait Asymmetry
Walking on Powered VR Shoes to Virtual Reality Motion
A User Experience Evaluation
Computational analysis of a theorised tendon-based trunk support device
Investigating safety, predictability, and mechanical requirements
Methods: To theoretically test if this device concept could meet the three criteria, a MATLAB simulation was written. A genetic optimization was then used to find the least stringent mechanical properties that still satisfy the three criteria. Off-the-shelf components that satisfy the mechanical properties were then found.
Results: Both pulley systems satisfied the safety and predictability criteria. Moreover, the necessary mechanical properties could be satisfied by off-the-shelf components, though some design modifications may be required. Ultimately, the configuration involving shorter ropes was determined to be the better option as it had less stringent mechanical requirements and potential design modifications would likely be easier to implement.
Conclusion: This study concluded that the optimised device, theoretically, shows good performance and seems practical to build. Future work is required to design a harness that would allow a child to comfortably train with the device. ...
Methods: To theoretically test if this device concept could meet the three criteria, a MATLAB simulation was written. A genetic optimization was then used to find the least stringent mechanical properties that still satisfy the three criteria. Off-the-shelf components that satisfy the mechanical properties were then found.
Results: Both pulley systems satisfied the safety and predictability criteria. Moreover, the necessary mechanical properties could be satisfied by off-the-shelf components, though some design modifications may be required. Ultimately, the configuration involving shorter ropes was determined to be the better option as it had less stringent mechanical requirements and potential design modifications would likely be easier to implement.
Conclusion: This study concluded that the optimised device, theoretically, shows good performance and seems practical to build. Future work is required to design a harness that would allow a child to comfortably train with the device.
This study investigates user perceptions of individualized versus standard and random gait patterns, focusing on enjoyment, comfort, and naturalness. A predictive gait pattern model, incorporating individual data and walking speed, was developed and tested with human participants using a grounded robotic lower limb device. Participants compared the three gait pattern types and provided subjective feedback through a questionnaire.
Findings indicate no significant preference for any gait pattern in terms of enjoyment, comfort, and naturalness, except for physical strain where the predicted pattern caused significantly more strain than the standard. The analysis also revealed that longer engagement with the device led to increased comfort and naturalness, suggesting an adaptation effect. A general tendency towards preferring the standard pattern was noted, though further research is necessary to determine whether a larger sample size reveals significant differences. Additionally, the perception of different gait patterns and their effect on the rehabilitation outcome should be explored with stroke patients. ...
This study investigates user perceptions of individualized versus standard and random gait patterns, focusing on enjoyment, comfort, and naturalness. A predictive gait pattern model, incorporating individual data and walking speed, was developed and tested with human participants using a grounded robotic lower limb device. Participants compared the three gait pattern types and provided subjective feedback through a questionnaire.
Findings indicate no significant preference for any gait pattern in terms of enjoyment, comfort, and naturalness, except for physical strain where the predicted pattern caused significantly more strain than the standard. The analysis also revealed that longer engagement with the device led to increased comfort and naturalness, suggesting an adaptation effect. A general tendency towards preferring the standard pattern was noted, though further research is necessary to determine whether a larger sample size reveals significant differences. Additionally, the perception of different gait patterns and their effect on the rehabilitation outcome should be explored with stroke patients.
Telerehabilitation of a Exoskeleton-haptic device System
Design and Evaluation on Stability and Transparency
The system provides a platform for further research on telerehabilitation and haptic communication in robotic rehabilitation. Working towards a system that allows the therapist, when desired, to intuitively interact with the patient while they are performing rehabilitation exercises using a robotic device. A modular telerehabilitation system is designed using the ARMin V (ETH Zurich) upper extremity exoskeleton as the patient side, and the haptic end-effector device Sigma.7 (Force Dimensions) as the therapist's side. A visualization is provided to the therapist side using Unity and additional features are added to improve usability. The telerehabilitation system is bilateral impedance controlled through a proportional-derivative controller.
An experiment is performed in which the observing participant is asked to resist motion (analyze stability) or to be compliant with the motion (analyze transparency).
The empirical analysis showed promising first results on position tracking, effective communication of haptic cues, stability, and transparency.
However, UDP communication rate could be raised, and the scaling of force and workspace between Sigma.7 and ARMin V could be better matched to improve transparency. ...
The system provides a platform for further research on telerehabilitation and haptic communication in robotic rehabilitation. Working towards a system that allows the therapist, when desired, to intuitively interact with the patient while they are performing rehabilitation exercises using a robotic device. A modular telerehabilitation system is designed using the ARMin V (ETH Zurich) upper extremity exoskeleton as the patient side, and the haptic end-effector device Sigma.7 (Force Dimensions) as the therapist's side. A visualization is provided to the therapist side using Unity and additional features are added to improve usability. The telerehabilitation system is bilateral impedance controlled through a proportional-derivative controller.
An experiment is performed in which the observing participant is asked to resist motion (analyze stability) or to be compliant with the motion (analyze transparency).
The empirical analysis showed promising first results on position tracking, effective communication of haptic cues, stability, and transparency.
However, UDP communication rate could be raised, and the scaling of force and workspace between Sigma.7 and ARMin V could be better matched to improve transparency.
Towards Personalization of Robot-Assisted Motor Learning Based on User Characteristics
Haptic Guidance seems better suited for individuals with a more Internal rather than External Locus of Control
We investigated the suitability of a haptic guidance feedback strategy, based on participants’ locus of control character trait, compared to training without haptic guidance. For this purpose, a motor learning experiment was conducted on 42 healthy participants, where the internal dynamics of a pendulum had to be learned in order to hit upcoming targets. For two groups, training either with or without haptic guidance, we assessed motor learning and its generalization to similar tasks through target hitting performance, as well as behavior during training and perceived user experience.
Evidence was found of a relatively better performance improvement in both training and long-term (generalization of) motor learning for participants with a more internal compared to external locus of control. Lower observed interaction force during training and increasingly better performance throughout training
in these participants may have caused these motor learning differences. More positive user experience in these individuals through a higher perceived control over the pendulum and lower perceived frustration with haptic guidance may have also contributed.
Combined, this suggests an intrinsically better compatibility
with haptic guidance for people with a more internal rather than
external locus of control, for motor learning, during training and
in user experience ...
We investigated the suitability of a haptic guidance feedback strategy, based on participants’ locus of control character trait, compared to training without haptic guidance. For this purpose, a motor learning experiment was conducted on 42 healthy participants, where the internal dynamics of a pendulum had to be learned in order to hit upcoming targets. For two groups, training either with or without haptic guidance, we assessed motor learning and its generalization to similar tasks through target hitting performance, as well as behavior during training and perceived user experience.
Evidence was found of a relatively better performance improvement in both training and long-term (generalization of) motor learning for participants with a more internal compared to external locus of control. Lower observed interaction force during training and increasingly better performance throughout training
in these participants may have caused these motor learning differences. More positive user experience in these individuals through a higher perceived control over the pendulum and lower perceived frustration with haptic guidance may have also contributed.
Combined, this suggests an intrinsically better compatibility
with haptic guidance for people with a more internal rather than
external locus of control, for motor learning, during training and
in user experience
Prior to this master thesis, a feasibility and usability study has been performed with the second iteration of the hand trainer in collaboration with therapists from Rijndam and healthy participants, showing room for improvement.
In this graduation project, the portable hand trainer is redesigned to develop an improved product design in comparison to the second iteration. Following a human-centered design approach, a modified version of the double diamond method was created to achieve a redesign that enables more functional, ergonomic, and motivating rehabilitation training.
Analysis on strokes, on rehabilitation, on the state-of-the-art, through peer tests, and on the usability study, were performed to create a decision matrix to define a list of potential improvements, distinguishing high-priority, medium-priority and low-priority improvements.
The high-priority improvements have been thoroughly addressed in multiple cycles of ideation-, developing- and validating activities. The results are combined and transformed into a hardware-ready 3D prototype that demonstrates improvement in the pronosupination movement, the donning and doffing of the device and the wrist support. The prototype of the third iteration of the portable hand trainer is evaluated through interviews with experts in the field to reflect on the project goal and propose recommendations on future work.
The medium-priority improvements have been addressed in one cycle of ideation activities of which the results are presented in sketches to advice on further development.
The low-priority improvements have not been addressed in this project. ...
Prior to this master thesis, a feasibility and usability study has been performed with the second iteration of the hand trainer in collaboration with therapists from Rijndam and healthy participants, showing room for improvement.
In this graduation project, the portable hand trainer is redesigned to develop an improved product design in comparison to the second iteration. Following a human-centered design approach, a modified version of the double diamond method was created to achieve a redesign that enables more functional, ergonomic, and motivating rehabilitation training.
Analysis on strokes, on rehabilitation, on the state-of-the-art, through peer tests, and on the usability study, were performed to create a decision matrix to define a list of potential improvements, distinguishing high-priority, medium-priority and low-priority improvements.
The high-priority improvements have been thoroughly addressed in multiple cycles of ideation-, developing- and validating activities. The results are combined and transformed into a hardware-ready 3D prototype that demonstrates improvement in the pronosupination movement, the donning and doffing of the device and the wrist support. The prototype of the third iteration of the portable hand trainer is evaluated through interviews with experts in the field to reflect on the project goal and propose recommendations on future work.
The medium-priority improvements have been addressed in one cycle of ideation activities of which the results are presented in sketches to advice on further development.
The low-priority improvements have not been addressed in this project.