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H.W. van Zeijl

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Seed production is a vital part of the global food supply chain. Seed surfaces are often contaminated with pathogenic fungal spores and bacteria, which cause plant diseases during germination. These pathogens prevent healthy crop growth and reduce yields by up to 40% in major crops. The future use of pesticides will be restricted by increasingly stringent regulations, while the demand for healthy crops continues to rise. Therefore, there is a growing need for eco-friendly technologies to inactivate seed-borne pathogenic microorganisms, without compromising seed quality. Cold atmospheric plasma (CAP) offers a promising alternative. Generated in ambient air, CAP is an ionized gas containing electrons, photons, ions, and reactive oxygen and nitrogen species (RONS). It does not leave toxic residues. Although CAP has demonstrated effective microbial inactivation at laboratory scale, its industrial implementation remains limited due to challenges in scalability, reliability and heat production. In this study, these limitations are addressed by developing and optimizing a wire-plate dielectric barrier discharge (DBD) for CAP seed disinfection, powered by high voltage pulses. The seed disinfection efficacy of the DBD was evaluated for cabbage and carrot seeds contaminated with bacteria (Xanthomonas campestris pv. campestris (Xcc) and Xanthomonas hortorum pv. carotae (Xhc)) and fungal spores (Alternaria brassicicola). Key parameters (such as treatment time, operating voltage and seed positioning) were investigated. The individual contribution of several plasma components (such as accelerated ions, RONS, pulsed electric fields) to seed disinfection was examined. Our results demonstrate that a large-area pulsed wire-plate DBD can achieve effective disinfection, while no reduction in seedling growth was observed. This highlights its potential as a scalable and sustainable alternative to conventional seed disinfection methods. ...
Low-temperature atmospheric plasma (LTP) is widely used in industrial processes, such as disinfection, surface modification and wastewater treatment. The dielectric barrier discharge (DBD) is regarded as one of the most robust and reliable methods for generating LTP in ambient air. Compared to conventional AC excitation, pulsed powering offers several advantages (i.e., lower energy use and heat production). The present trend is to use short and fast pulses (in the nano- and picosecond range). In this review, the key design parameters of a DBD (barrier thickness, relative permittivity and gap distance) are discussed. Material-specific phenomena like surface charging and degradation are analyzed. The complex interactions between the pulse source and DBD are examined. By mapping the interdependencies, this review aims to support the rational design and optimization of pulsed DBD systems, and to facilitate their broader industrial use. ...
The paper presents a degradation for remaining useful lifetime framework for smart power stages (SPS) with an integrated temperature sensor for electronic control units (ECU). A reduced order state space model with physically meaningful time constants is derived from finite element simulations. The state space model is the core of the damage estimation of the SPS during operation. A framework for remaining useful lifetime estimation is presented simulating degradation based on an estimated mission profile for cars. Temperature cycles are extracted and used to estimate the time constant drift representing package degradation. An exemplary approach on how to integrate degradation monitoring into a lifetime approximation of the package is presented. The state space model is extended for estimator based predictions to integrate the model in future test benches for real life monitoring and remaining useful life predictions of active devices. ...

An experimental study of mounting-pressure effects in microchip assembly

This work presents an experimental investigation of adhesive-based die attachment using the Drop-Attach technique, compared with the conventional pick-and-place method. Drop-Attach is a contactless process that eliminates the mechanical stresses inherent to force-assisted placement. In this method, dies are optically aligned and released—via a short air pulse—from a height of 100–300 μm above a substrate coated with a flat adhesive layer, enabling pressure-free, contactless placement. The process achieves smaller cycle times, potentially improving the throughput over conventional methods that require additional time for deceleration and bonding-force buildup. To assess feasibility and performance, a silver-filled bismaleimide/acrylate adhesive was printed on ENIG-finished pads, and dummy silicon dies with Au-, Ag-, and Cu-coated surfaces were assembled using both techniques. Bond quality was comprehensively analysed through measurements of bond line thickness, die tilt, void formation, die-shear strength, failure mechanisms, and electrical performance. Drop-Attach achieved minimal die tilt (≤0.1°) and uniform BLTs, though higher voiding and ∼9.55% increased electrical resistance were observed. The lower shear strength was primarily attributed to the absence of adhesive fillet formation rather than the lack of applied pressure. While trade-offs remain, this study demonstrates the feasibility of adhesive-based die attachment using the Drop-Attach method, which enables faster cycle times and higher throughput while significantly reducing mechanical stresses. These advantages position Drop-Attach as a promising technique for next-generation semiconductor packaging. ...
Cold atmospheric plasma (CAP) is widely used in domains such as disinfection, surface treatment and food preservation. When generated in air, CAP is rich in reactive oxygen and nitrogen species (RONS), such as ozone (O3). A dielectric barrier discharge (DBD) is a reliable method to create CAP. We developed a double-sided (twin) surface DBD with novel ‘interfractal’ electrode geometries. This fractal configuration creates stronger electric fields than the customary interdigital line geometry. So, CAP is produced more effectively, resulting in higher RONS concentrations. The performance of interfractal electrodes was compared to that of interdigital electrodes (IDE) in atmospheric air. Nanopulsed powering was used, since it is the most efficient for powering DBDs. Electrical and chemical characteristics (such as ozone level) were assessed. The results show that interfractal electrodes enhance the electric field, conduction current and ozone yield. ...
Conference paper (2025) - Lai Wei, Sander Dorrestein, Henk van Zeijl, Guoqi Zhang
This study presents a novel approach for localized silver (Ag) nanoparticles (NPs) sintering using microheater arrays embedded within the Si substrate. By applying controlled pulse currents, these microheaters generate targeted heat pulses, enabling rapid and localized sintering while maintaining the surrounding device components at room temperature. This localized heating minimizes thermal stress caused by thermal expansion mismatches, as sintering completes within milliseconds. Compared to conventional sintering techniques, this method improves process efficiency, reduces power consumption, and provides precise spatial control over the sintered regions. The proposed approach offers a promising alternative for microelectronics packaging and integration, particularly in applications requiring precise thermal management. ...
This article presents a novel in-package relative humidity (RH) sensor designed to enhance moisture detection within the chip encapsulation material, specifically epoxy molding compound (EMC). Traditional methods for assessing EMC moisture content, such as mass measurements, are time-consuming and incompatible with industrial reliability tests, limiting their use for real-time, in situ monitoring. To address these challenges, we propose an integrated capacitive sensor that directly measures moisture content within the encapsulation material. The sensor utilizes a heterogeneous electrode design to overcome the sensitivity limitations of conventional interdigital electrodes (IDEs). This design features sections of different widths, allowing selective wet chemical etching of the silicon dioxide layer using buffered hydrofluoric acid (BHF). By controlling the etching time, the silicon dioxide layer beneath the narrower sections is completely etched, while oxide pillars form under the wider sections, resulting in semifloating electrodes. The EMC fills the etched regions and wraps around the narrower sections, concentrating more electric field lines in the EMC and enhancing sensor sensitivity. Our proposed sensor achieves a capacitance change of 1 pF per 80% RH, improving sensitivity from 6.9 to 12.3 fF/%RH, with a 20% increase in relative capacitance change. A shielding layer is added to minimize parasitic capacitance effects, ensuring accurate measurements. The proposed sensor is fully CMOS-compatible and can monitor moisture-induced reliability risks, as well as assess packaging material aging. This work provides a cost-effective and reliable solution for in-package humidity monitoring in semiconductor applications. ...
Journal article (2025) - M. Yazdan Mehr, P. Hajipour, M. R. Karampoor, H. van Zeijl, W. D. van Driel, T. Cooremans, F. De Buyl, G. Q. Zhang
This paper investigates the effects of three ageing factors (chemical, humidity, and temperature) and their interactions on the physical properties and degradation of silicone sealant used in microelectronic applications. The thermal degradation of silicone sealants was investigated by exposing samples to temperatures in the range of 150 up to 175 °C. Also, a set of samples were aged at 40 °C in a salt spray set-up with 100 % humidity in a salty atmosphere. Results showed detectable changes in the FTIR spectra of aged specimen as compared with the as-received sample. In all accelerated testing conditions, peak intensities decreased with ageing time, inferring that that the surface characteristics of the sealant is affected by ageing. Shear test results showed that with increasing the ageing time, the maximum shear stress in most cases has decreased in all ageing conditions. Also, it appears that samples with longer ageing times have experienced more elongation before failure. Results also show that salt spraying of specimens is associated with a decrease in the mechanical properties of the sealant, indicating the deleterious implications of ionic contaminations for the mechanical properties of samples. ...
Conference paper (2024) - Xinrui Ji, Leiming Du, Henk Van Zeijl, Guoqi Zhang, Jaber Derakhshandeh, Eric Beyne
This report demonstrates an innovative method to achieve large scale 20 μm pitch Cu-Cu direct bonding, utilizing lithographic stencil printing to transfer small-sized nano-copper (CuNPs) paste and employs a thermocompression method for CuNPs sintering to establish interconnections between copper-pillars and CuNPs bumps. Shear tests were conducted to characterize the bonding strength. High-throughput 20 μm pitch copper-to-copper direct bonding enables lower annealing temperatures for bulk-Cu to bulk-Cu bonding. Lithographic stencil printing is used to transfer the CuNPs paste, followed by sintering of the nanoparticles to establish interconnections. Shear tests and cross-section SEM were conducted to characterize the bonding strength and quality. ...
Power MOSFET dies in the automotive industry are becoming larger (>5 × 5 mm) and thinner (<50 µm) to meet high-performance and lifetime requirements. Ensuring the mechanical robustness of these large ultrathin chips is crucial for reliable electronic devices and high-throughput packaging processes. The high aspect ratio and advanced chip designs incorporating trench technology present significant challenges in semiconductor assembly, packaging, and testing. This paper introduces an experimental front-end strategy aimed at strengthening the front side (FS) of large ultrathin dies using various die-top systems. Industry-equivalent 50 µm thick dummy power MOSFET dies were fabricated to evaluate the efficacy of different chip designs and materials, such as polyimide (PI), in mitigating fracture risks. Fabrication-induced stresses and warpage in the device layers were measured using a thin-film stress measurement tool. Additionally, the FS strength of the ultrathin dies was assessed using the three-point bending method, with the resulting data analyzed via two-parameter Weibull distribution plots. Results demonstrated that the deposition of 5 µm PI on the nitride die topside significantly increased die strength from 339 MPa to 760 MPa, with 5 µm PI proving more effective for die strengthening than 10 µm. The interaction between the metal-trench layer and the die was found to be critical to the robustness of ultrathin dies, influenced by the pattern and layout of the trenches. Die-top metallization designs, such as meandering patterns, showed promising improvements in die strength compared to standard designs. A proposed chip layout aims to maximize PI coverage for clip-bonded products on the die topside, leveraging its strengthening effect. The study also demonstrated that dummy reference chips can facilitate rapid and straightforward evaluation of extensive design experiments to identify robust chip designs. ...
Journal article (2023) - Joost Romijn, Sten Vollebregt, Pasqualina M. Sarro, Vincent G. de Bie, Luke M. Middelburg, Brahim El Mansouri, Henk W. van Zeijl, Alexander May, Tobias Erlbacher, Johan Leijtens, Guoqi Zhang
The next generation of satellites will need to tackle tomorrow's challenges for communication, navigation and observation. In order to do so, it is expected that the amount of satellites in orbit will keep increasing, form smart constellations and miniaturize individual satellites to make access to space cost effective. To enable this next generation of activities in space, it is vital to ensure the ability of these satellites to properly navigate themselves. This control starts with attitude measurement by the dedicated sensors on the satellite, commonly performed by sun position sensors. The state-of-the art is confronted by large signal distortions caused by light reflected by the Earth's albedo as well as keeping up with the satellite miniaturization trend. This work aims to address both these issues, by presenting a microfabricated albedo insensitive sun position sensor in silicon carbide with wafer-level integrated optics. The presented 10 mm×10 mm×1 mm system reaches a mean angular accuracy of 5.7° in a ±37° field-of-view and integrates an on-chip temperature sensor with a -3.9 mV K−1 sensitivity in the 20 °C to 200 °C range. ...
Conference paper (2023) - Romina Sattari, Henk van Zeijl, Guoqi Zhang
This study presents a novel manufacturing process and design towards an enhanced sensitivity of an in-package relative humidity sensor. The device comprises multi-width interdigital electrodes which make oxide pillars appear during wet chemical etching in the fabrication process. Those oxide pillars appear only in wider areas while completely etched away in narrower areas providing semi-floating metal fingers. Therefore, after wafer molding, the packaging encapsulation material such as the epoxy molding compound covers larger area around the electrodes and increases the sensitivity by confining more of the electrical field lines. The results confirm the enhanced sensitivity of the proposed humidity sensor for characterization and monitoring of the aging properties of packaging encapsulation materials. ...
Conference paper (2023) - Romina Sattari, Henk van Zeijl, Guoqi Zhang
This study presents the design and fabrication of an in-package relative humidity sensor for epoxy molding compound (EMC) packages. The sensor comprises shielded interdigital electrodes (SIDE) for in-situ monitoring of humidity absorption/desorption in the package encapsulation layer. A novel approach is employed in the device fabrication to maximize the electrical field lines to pass through the EMC and enhance the sensitivity. The manufactured wafer includes 6×6mm2 dies, each containing six identical capacitive sensors with an area of 480 × 620 μ m2. SU-8 through polymer vias (TPVs) with high aspect ratio were created to locally mold the sensors by EMC. The linear capacitance change with the relative humidity level is simulated in COMSOL Multiphysics. Three designs were compared, and the calibration results show the capacitance value of 1.54 pF and 5.85 pF before and after molding, respectively. The capacitance value stays within the range of 5.85 to 5.86 pF with less than 7 aF variation under different biasing voltages, indicating the stability and robustness of the capacitance. ...
Conference paper (2023) - Romina Sattari, Henk van Zeijl, Guoqi Zhang
This paper reports the design and fabrication of a 4H-SiC CMOS readout circuit enabling monolithic integration of silicon carbide (SiC) sensors and circuits. Compared to conventional Si electronics, 4H-SiC integrated circuits can sustain operation in harsh conditions such as higher temperatures and radiation levels. The proposed amplifier performance is well balanced through the temperature range of 25 °C to 400 °C. Compared to state-of-the-art, the proposed SiC readout circuit does not include any off-chip components. The amplifier is fully differential, and hence shows improved common-mode rejection and signal-to-noise ratio (SNR). It can be monolithically integrated with SiC sensors in a scalable SiC technology. ...
Conference paper (2023) - Romina Sattari, Henk Van Zeijl, Guoqi Zhang
Wide bandgap (WBG) semiconductor technologies enable significant progress in the emergence of power modules. Power cycling at elevated temperatures causes crack or delamination failure, especially at the die-attached bonded interface in the long term. Therefore, the in-situ reliability investigation of power modules, materials, and semiconductor packages is of great significance for modern industries. The silicon carbide's higher bandgap energy, intrinsic thermal conductivity, and mechanical strength make it a great candidate for the next generation of semiconductor, designed to operate in harsh conditions. In this study, a thin-film reconfigurable silicon carbide (SiC) thermal test chip (TTC) is designed and fabricated for reliability assessment in harsh environments. The proposed TTC realizes in-situ power/thermal cycling tests at elevated temperatures as well as characterization of novel materials such as nanoparticle-based sintering materials in die-attach technology and high-temperature-compatible epoxy molding compounds. The chip is equipped with thin-film platinum microheaters to realize modular power mappings, and platinum resistive temperature detectors (RTD) to examine the thermal reliability by monitoring the precise changes of the internal junction-to-case thermal resistance. ...
The rapid development of power electronics has challenged the thermal integrity of semiconductor packaging. Further developments in this domain can be supported significantly by utilizing fast and flexible thermal characteristic evaluation. This study employs the transient dual interface method (TDIM) to characterize and compare the thermal resistance of Ag- and Cu-sintered die-attach joints using an in-house developed thermal test chip (TTC). The proposed TTC with 82.5% active area achieves a temperature sensitivity of 12 Ω/K and maximum power of 360 W per cell, which are 50% and 44% higher than the state-of-the-art, respectively. The uniformity of the temperature distribution (1 °C at 68 W) is verified by infrared thermography. The cost-effective manufacturing process allows the design to be applied to any substrate, such as SiC or GaN. Ag and Cu sintering is performed to bond the TTC on a Cu substrate, and the junction-to-case thermal resistance of the sintered structures is extracted. The lowest junction-to-case thermal resistance of 0.144 K/W is measured for the device sintered using Ag paste. Meanwhile, the Cu sintered structure exhibits a comparable value of 0.158 K/W. The proposed TTC in combination with TDIM accelerates the introduction of novel and cost-effective materials such as Cu. ...
Micro-devices that use electric fields to trap, analyze and inactivate micro-organisms vary in concept, design and application. The application of electric fields to manipulate and inactivate bacteria and single-celled organisms has been described extensively in the literature. By contrast, the effect of such fields on viruses is not well understood. This review explores the possibility of using existing methods for manipulating and inactivating larger viruses and bacteria, for smaller viruses, such as SARS-CoV-2. It also provides an overview of the theoretical background. The findings may be used to implement new ideas and frame experimental parameters that optimize the manipulation, sampling and inactivation of SARS-CoV-2 electrically. ...
Conference paper (2023) - Maryam Yazdan Mehr, Pejman Hajipour, H. van Zeijl, W.D. van Driel, Thierry Cooremans, Francois De Buyl, G.Q. Zhang
Adhesive bonding is a key joining technology in many industrial applications, including automotive, aerospace industries, biomedical devices, and microelectronic components. Adhesive bonding is gaining more and more attention due to the increasing demand for joining similar or dissimilar components, mostly within the framework of designing lightweight structures. Silicone sealant is widely used in engineering application due to its thermal stability, excellent energy absorption, and good damping characteristics. In those applications, sealant usually exposed to various environment stress, such as, high temperature, mechanical stress, humidity, light radiation, and chemical attack. Long-term stability and durability of sealant is crucial to the performance of the associated application. The main degrading factors for silicone in microelectronic applications are temperature, humidity, alkali, and mechanical loading. The focus in the present paper is to understand different failure mechanisms in silicone sealants and adhesives and to study how different environmental, mechanical, and service-related stresses attribute to the kinetics and extent of degradation in silicone sealants and adhesives. The impact of different failure mechanisms on the lifetime and reliability of microelectronic devices will be methodically investigated. ...
Conference paper (2023) - Baoyun Sun, Jiarui Mo, Hemin Zhang, Henk W. van Zeijl, Willem D. van Driel, Guoqi Zhang
The thermal-piezoresistive effect in silicon (Si) has attracted great attention toward high-performance resonant devices but still faces major challenges for harsh environment applications. Instead of using Si, this paper, for the first time, reports a thermal-piezoresistive resonator based on a silicon carbide-on-insulator (SiCOI) platform. The resonance frequency simulation, CMOS-compatible fabrication, and thermoresistive properties characterization of the proposed SiCOI resonator are presented. The experimental results show linear current-voltage characteristics and a constant temperature coefficient of resistance (TCR) up to 200 °C. ...
The trend to 3D and heterogeneous integration enable driving multi-functional blocks in one package. Flip-chip integration is currently playing an important role and is based on solder joints. To overcome the limitations of solder joints, all-copper interconnects have been investigated to meet electrical, thermal, and reliability demands in 3D integration. The underfill process is widely applied in flip-chip encapsulation technology. We propose a novel wafer-scale all-Cu interconnect method combining epoxy-based photo-patternable polymer as self-aligned underfill layer with the patterned copper nanoparticles interconnects. The resulting test wafers were able to pattern 20 µm pitch copper nanoparticle-paste interconnects on both substrates with and without photoimageable polymer. The Cu paste was applied to form the interconnects and was sintered after bonding process. Free-standing nanocopper is sintered to obtain mechanical properties with a Young's modulus of 112 GPa. All-Cu interconnects with diameter of 50 µm and 100 µm were measured to achieve the specific contact resistance, ranging from 1.4 × 10-5O· cm2 to 1.0 × 10-5O· cm2 at different sintering temperature when epoxy-based underfill existing. And its resistivity was 4.54× 10-4 O· cm, compared to 5.86× 10-4O· cn for the all-Cu interconnects without underfill. ...